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Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Kempster, C., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Mitchell, J. L., Sage, T., Rawlings, S., Diaz Alonso, M. V., Shpakova, V. orcid id iconORCID: https://orcid.org/0000-0002-9304-7099, Whyte, A., Dymott, L., Mark, S., Brunton, M., Batista, J., McKinney, H., Thomas, P., Downes, K., Unsworth, A. J., Ruparelia, N., McKenna, C., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2025) TRIPLE score: GPVI and CD36 expression predict a prothrombotic platelet function phenotype. Circulation Research, 136 (4). pp. 439-441. ISSN 0009-7330 doi: 10.1161/CIRCRESAHA.124.325701

Mitchell, J. L., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) The rate of platelet activation determines thrombus size and structure at arterial shear. Journal of Thrombosis and Haemostasis, 21 (8). pp. 2248-2259. ISSN 1538-7836 doi: 10.1016/j.jtha.2023.03.044

Kuravi, S. J., Ahmed, N. S., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Capes, E. M., Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Pugh, N. (2023) Delineating zinc influx mechanisms during platelet activation. International Journal of Molecular Sciences, 24 (14). 11689. ISSN 1422-0067 doi: 10.3390/ijms241411689

Mitchell, J. L., Little, G., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability. Research and Practice in Thrombosis and Haemostasis, 7 (5). 100200. ISSN 2475-0379 doi: 10.1016/j.rpth.2023.100200

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Rawlings, S. J., Prodger, C., Kesavan, M., Lees, C., Booth, S., Cowen, L. G., Shefferd, K., Desborough, M. J., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Eyre, T. A. (2023) Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib. Haematologica, 108 (5). ISSN 1592-8721 doi: 10.3324/haematol.2022.281402

Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2023) Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets, 34 (1). 2264940. ISSN 1369-1635 doi: 10.1080/09537104.2023.2264940

Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. orcid id iconORCID: https://orcid.org/0000-0003-3809-5984 (2022) Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function. Thrombosis and Haemostasis, 122 (07). pp. 1115-1129. ISSN 0340-6245 doi: 10.1055/a-1788-5322

Dunster, J. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances, 5 (20). pp. 4017-4030. ISSN 2473-9529 doi: 10.1182/bloodadvances.2020003261

Alatawi, K., Ravishankar, D., Patra, P., Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Stainer, A., Patel, K., Widera, D. orcid id iconORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517 (2021) 1,8-cineole affects agonists-induced platelet activation, thrombus formation and haemostasis. Cells, 10 (10). 2616. ISSN 2073-4409 doi: 10.3390/cells10102616

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S. orcid id iconORCID: https://orcid.org/0009-0000-8886-6893, Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. orcid id iconORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets. Blood, 138 (16). pp. 1481-1489. ISSN 0006-4971 doi: 10.1182/blood.2021011871

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: 10.3324/haematol.2019.223529

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. orcid id iconORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: 10.1182/blood.2019004575

Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. orcid id iconORCID: https://orcid.org/0000-0001-8706-5154 (2020) Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation. Journal of Thrombosis and Haemostasis, 18 (2). pp. 485-496. ISSN 1538-7836 doi: 10.1111/jth.14673

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (2020) Ca2+ waves coordinate purinergic receptor–evoked integrin activation and polarization. Science Signaling, 13 (615). eaav7354. ISSN 1937-9145 doi: 10.1126/scisignal.aav7354

Stainer, A., Sasikumar, P., Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. orcid id iconORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: 10.1080/09537104.2018.1514107

Stainer, A. R., Sasikumar, P., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. orcid id iconORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis, 16 (8). pp. 1461-1463. ISSN 1538-7933 doi: 10.1111/jth.14201

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: 10.1111/jth.13998

Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Ilkan, Z., Unsworth, A. and Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2018) Immobilization of nonactivated unfixed platelets for real-time single-cell analysis. In: Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes (Volume 4, Advanced Protocols and Perspectives). Methods in Molecular Biology, 1812. Springer Protocols, pp. 1-11. ISBN 9781493985845

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_5

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. orcid id iconORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: 10.1182/bloodadvances.2017011999

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P. orcid id iconORCID: https://orcid.org/0000-0002-6716-7599, Warner, T. D., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets. Arteriosclerosis, thrombosis, and vascular biology, 37 (8). pp. 1482-1493. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309135

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309207

Unsworth, A. J., Kriek, N., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. Journal of Thrombosis and Haemostasis, 15 (2). pp. 356-369. ISSN 1538-7933 doi: 10.1111/jth.13578

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: 10.1161/ATVBAHA.116.308093

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2016) Platelet signaling: a complex interplay between inhibitory and activatory networks. Journal of Thrombosis and Haemostasis, 14 (5). pp. 918-930. ISSN 1538-7933 doi: 10.1111/jth.13302

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: 10.1161/ATVBAHA.115.306130

This list was generated on Sat Oct 11 08:18:17 2025 UTC.