Items where Author is "Kriek, Dr Neline"

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Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Kempster, C., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Mitchell, J. L., Sage, T., Rawlings, S., Diaz Alonso, M. V., Shpakova, V. orcid id iconORCID: https://orcid.org/0000-0002-9304-7099, Whyte, A., Dymott, L., Mark, S., Brunton, M., Batista, J., McKinney, H., Thomas, P., Downes, K., Unsworth, A. J., Ruparelia, N., McKenna, C., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2025) TRIPLE score: GPVI and CD36 expression predict a prothrombotic platelet function phenotype. Circulation Research, 136 (4). pp. 439-441. ISSN 0009-7330 doi: 10.1161/CIRCRESAHA.124.325701

Mitchell, J. L., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) The rate of platelet activation determines thrombus size and structure at arterial shear. Journal of Thrombosis and Haemostasis, 21 (8). pp. 2248-2259. ISSN 1538-7836 doi: 10.1016/j.jtha.2023.03.044

Mitchell, J. L., Little, G., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability. Research and Practice in Thrombosis and Haemostasis, 7 (5). 100200. ISSN 2475-0379 doi: 10.1016/j.rpth.2023.100200

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Rawlings, S. J., Prodger, C., Kesavan, M., Lees, C., Booth, S., Cowen, L. G., Shefferd, K., Desborough, M. J., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Eyre, T. A. (2023) Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib. Haematologica, 108 (5). ISSN 1592-8721 doi: 10.3324/haematol.2022.281402

Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2023) Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets, 34 (1). 2264940. ISSN 1369-1635 doi: 10.1080/09537104.2023.2264940

Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. orcid id iconORCID: https://orcid.org/0000-0003-3809-5984 (2022) Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function. Thrombosis and Haemostasis, 122 (07). pp. 1115-1129. ISSN 0340-6245 doi: 10.1055/a-1788-5322

Downes, K., Zhao, X., Gleadall, N. S., Antanavicius, N., McKinney, H., Kempster, C., Batista, J., Thomas, P. L., Cooper, M., Michael, J. V., Kreuzhuber, R., Wedderburn, K., Waller, K., Varney, B., Kriek, N., Ashford, S. E., Stirrups, K. E., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, McKenzie, S. E., Ouwehand, W. H., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352, Yang, J., Astle, W. J. and Ma, P. (2022) G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Advances, 6 (7). pp. 2319-2330. ISSN 2473-9529 doi: 10.1182/bloodadvances.2021005453

Kempster, C., Butler, G., Kuznecova, E., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Kriek, N., Little, G., Sowa, M. A., Sage, T., Johnson, L. J. orcid id iconORCID: https://orcid.org/0000-0002-0006-1511, Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. orcid id iconORCID: https://orcid.org/0000-0001-8706-5154 (2022) Fully automated platelet differential interference contrast image analysis via deep learning. Scientific Reports, 12. 4614. ISSN 2045-2322 doi: 10.1038/s41598-022-08613-2

Dunster, J. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances, 5 (20). pp. 4017-4030. ISSN 2473-9529 doi: 10.1182/bloodadvances.2020003261

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S. orcid id iconORCID: https://orcid.org/0009-0000-8886-6893, Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. orcid id iconORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets. Blood, 138 (16). pp. 1481-1489. ISSN 0006-4971 doi: 10.1182/blood.2021011871

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: 10.3324/haematol.2019.223529

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: 10.3390/antiox10030497

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. orcid id iconORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: 10.1182/blood.2019004575

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: 10.1080/09537104.2018.1514107

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: 10.1111/jth.13998

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. orcid id iconORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: 10.1182/bloodadvances.2017011999

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P. orcid id iconORCID: https://orcid.org/0000-0002-6716-7599, Warner, T. D., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets. Arteriosclerosis, thrombosis, and vascular biology, 37 (8). pp. 1482-1493. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309135

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309207

Unsworth, A. J., Kriek, N., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. Journal of Thrombosis and Haemostasis, 15 (2). pp. 356-369. ISSN 1538-7933 doi: 10.1111/jth.13578

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: 10.1161/ATVBAHA.116.308093

Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: 10.1182/blood-2014-06-585083

Moraes, L. A., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: 10.1182/blood-2013-04-491845

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