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Mitchell, J. L., Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) The rate of platelet activation determines thrombus size and structure at arterial shear. Journal of Thrombosis and Haemostasis, 21 (8). pp. 2248-2259. ISSN 1538-7836 doi: 10.1016/j.jtha.2023.03.044

Kuravi, S. J., Ahmed, N. S., Taylor, K. A. orcid id iconORCID: https://orcid.org/0000-0002-4599-7727, Capes, E. M., Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Pugh, N. (2023) Delineating zinc influx mechanisms during platelet activation. International Journal of Molecular Sciences, 24 (14). 11689. ISSN 1422-0067 doi: 10.3390/ijms241411689

Mitchell, J. L., Little, G., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2023) Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability. Research and Practice in Thrombosis and Haemostasis, 7 (5). 100200. ISSN 2475-0379 doi: 10.1016/j.rpth.2023.100200

Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2023) Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets, 34 (1). 2264940. ISSN 1369-1635 doi: 10.1080/09537104.2023.2264940

Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. orcid id iconORCID: https://orcid.org/0000-0003-3809-5984 (2022) Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function. Thrombosis and Haemostasis, 122 (07). pp. 1115-1129. ISSN 0340-6245 doi: 10.1055/a-1788-5322

Dunster, J. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances, 5 (20). pp. 4017-4030. ISSN 2473-9529 doi: 10.1182/bloodadvances.2020003261

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: 10.3324/haematol.2019.223529

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. orcid id iconORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: 10.1182/blood.2019004575

Dunster, J. L. orcid id iconORCID: https://orcid.org/0000-0001-8986-4902, Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. orcid id iconORCID: https://orcid.org/0000-0001-8706-5154 (2020) Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation. Journal of Thrombosis and Haemostasis, 18 (2). pp. 485-496. ISSN 1538-7836 doi: 10.1111/jth.14673

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: 10.1038/s41598-019-53218-x

Stainer, A., Sasikumar, P., Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. orcid id iconORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Unsworth, A. J., Bombik, I., Pinto-Fernandez, A., McGouran, J. F., Konietzny, R., Zahedi, R. P., Watson, S. P., Kessler, B. M. and Pears, C. J. (2019) Human platelet protein ubiquitylation and changes following GPVI activation. Thrombosis and Haemostasis, 119 (1). pp. 104-116. ISSN 0340-6245 doi: 10.1055/s-0038-1676344

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: 10.1080/09537104.2018.1514107

Stainer, A. R., Sasikumar, P., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. orcid id iconORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2019) The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: 10.1111/jth.13998

Unsworth, A. J., Flora, G. D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) Non-genomic effects of nuclear receptors: insights from the anucleate platelet. Cardiovascular Research, 114 (5). pp. 645-655. ISSN 0008-6363 doi: 10.1093/cvr/cvy044

Bye, A. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Ilkan, Z., Unsworth, A. and Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 (2018) Immobilization of nonactivated unfixed platelets for real-time single-cell analysis. In: Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes (Volume 4, Advanced Protocols and Perspectives). Methods in Molecular Biology, 1812. Springer Protocols, pp. 1-11. ISBN 9781493985845

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_5

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. orcid id iconORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: 10.1182/bloodadvances.2017011999

Unsworth, A. J., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P. orcid id iconORCID: https://orcid.org/0000-0002-6716-7599, Warner, T. D., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets. Arteriosclerosis, thrombosis, and vascular biology, 37 (8). pp. 1482-1493. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309135

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309207

Unsworth, A. J., Kriek, N., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2017) PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. Journal of Thrombosis and Haemostasis, 15 (2). pp. 356-369. ISSN 1538-7933 doi: 10.1111/jth.13578

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: 10.1161/ATVBAHA.116.308093

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2016) Platelet signaling: a complex interplay between inhibitory and activatory networks. Journal of Thrombosis and Haemostasis, 14 (5). pp. 918-930. ISSN 1538-7933 doi: 10.1111/jth.13302

Bye, A. P. orcid id iconORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: 10.1161/ATVBAHA.115.306130

Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2015) Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology, 172 (16). pp. 4133-4145. ISSN 0007-1188 doi: 10.1111/bph.13191

Vaiyapuri, S. orcid id iconORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. orcid id iconORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: 10.1182/blood-2014-06-585083

This list was generated on Sat Oct 11 08:18:39 2025 UTC.