Items where Author is "Spencer, Professor Jeremy"

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Number of items: 144.

Mekhora, C., Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2024) Effect of polyphenols on inflammation related to cognitive function: a systematic review and meta-analysis of human randomized controlled trials. Nutrition and Healthy Aging, 9 (1). pp. 113-131. ISSN 2451-9502 doi: 10.3233/NHA-240006

ALbuloshi, T. ORCID: https://orcid.org/0000-0002-4609-3623, Kamel, A. M. ORCID: https://orcid.org/0000-0002-3791-5998 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2022) Factors associated with low vitamin D status among older adults in Kuwait. Nutrients, 14 (16). 3342. ISSN 2072-6643 doi: 10.3390/nu14163342

Albuloshi, T., Dimala, C. A., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Bouhaimed, M., Dodd, G. F. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2022) The effectiveness of vitamin D supplementation in reducing depressive symptoms: a systematic review and meta-analysis of Randomized Controlled Trials (RCTs). Nutrition and Healthy Aging, 6 (4). pp. 301-318. ISSN 2451-9502 doi: 10.3233/nha-200094

Huarte, E. ORCID: https://orcid.org/0000-0002-8492-1805, Serra, G., Monteagudo-Mera, A., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Cid, C. ORCID: https://orcid.org/0000-0001-6464-5412 and de Peña, M.-P. ORCID: https://orcid.org/0000-0002-9994-4268 (2021) Raw and sous-vide-cooked red cardoon stalks (cynara cardunculus L. var. altilis DC): (poly)phenol bioaccessibility, anti-inflammatory activity in the gastrointestinal tract, and prebiotic activity. Journal of Agricultural and Food Chemistry, 69 (32). pp. 9270-9286. ISSN 1520-5118 doi: 10.1021/acs.jafc.1c03014

Turner, A. L., Michaelson, L. V., Shewry, P. R., Lovegrove, A. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2021) Increased bioavailability of phenolic acids and enhanced vascular function following intake of feruloyl esterase-processed high fibre bread: a randomized, controlled, single blind, crossover human intervention trial. Clinical Nutrition, 40 (3). pp. 788-795. ISSN 0261-5614 doi: 10.1016/j.clnu.2020.07.026

Vauzour, D., Rendeiro, C., D'Amato, A., Waffo-Teguo, P., Richard, T., Merillon, J. M., Pontifex, M. G., Connell, E., Muller, M., Butler, L. T., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2021) Anthocyanins promote learning through modulation of synaptic plasticity related proteins in an animal model of ageing. Antioxidants, 10 (8). 1235. ISSN 2076-3921 doi: 10.3390/antiox10081235

Flanagan, E., Lamport, D. ORCID: https://orcid.org/0000-0002-4592-0439, Brennan, L., Burnet, P., Calabrese, V., Cunnane, S. C., de Wilde, M. C., Dye, L., Farrimond, J. A., Emerson Lombardo, N., Hartmann, T., Hartung, T., Kalliomäki, M., Kuhnle, G. G. ORCID: https://orcid.org/0000-0002-8081-8931, La Fata, G., Sala-Vila, A., Samieri, C., Smith, A. D., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Thuret, S., Tuohy, K., Turroni, S., Vanden Berghe, W., Verkuijl, M., Verzijden, K., Yannakoulia, M., Geurts, L. and Vauzour, D. (2020) Nutrition and the ageing brain: moving towards clinical applications. Ageing Research Reviews, 62. 101079. ISSN 1568-1637 doi: 10.1016/j.arr.2020.101079

Alañón, M. E., Castle, S. M., Serra, G., Lévèques, A., Poquet, L., Actis-Goretta, L. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2020) Acute study of dose-dependent effects of (-)-epicatechin on vascular function in healthy male volunteers: a randomized controlled trial. Clinical Nutrition, 39 (3). pp. 746-754. ISSN 0261-5614 doi: 10.1016/j.clnu.2019.03.041

Bell, L. ORCID: https://orcid.org/0000-0003-0677-021X, Whyte, A. R., Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Butler, L. T. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2020) Grape seed polyphenol extract and cognitive function in healthy young adults: A randomised, placebo-controlled, parallel-groups acute-on-chronic trial. Nutritional Neuroscience, 25 (1). pp. 54-63. ISSN 1028-415X doi: 10.1080/1028415X.2019.1708033

Soycan, G., Schar, M., Kristek, A., Boberska, J., Alsharif, S. N. S., Corona, G., Shewry, P. R. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2019) Composition and content of phenolic acids and avenanthramides in commercial oat products: are oats an important polyphenol source for consumers? Food Chemistry: X, 3. 100047. ISSN 2590-1575 doi: 10.1016/j.fochx.2019.100047

Dodd, G. F., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Butler, L. T. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2019) Acute effects of flavonoid-rich blueberry on cognitive and vascular function in healthy older adults. Nutrition and Healthy Aging, 5 (2). pp. 119-132. ISSN 2451-9502 doi: 10.3233/nha-180056

Mascal, M., Hafezi, N., Wang, D., Hu, Y., Serra, G., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2019) Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures. Scientific Reports, 9 (1). 7778. ISSN 2045-2322 doi: 10.1038/s41598-019-44056-y

Kristek, A., Wiese, M., Heuer, P., Kosik, O., Schar, M. Y., Soycan, G., Alsharif, S., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2019) Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota. British Journal of Nutrition, 121 (5). pp. 549-559. ISSN 0007-1145 doi: 10.1017/S0007114518003501

Kristek, A., Schar, M. Y., Soycan, G., Alsharif, S., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2018) The gut microbiota and cardiovascular health benefits: a focus on wholegrain oats. Nutrition Bulletin, 43 (4). pp. 358-373. ISSN 1471-9827 doi: 10.1111/nbu.12354

Baldrick, F. R., McFadden, K., Ibars, M., Sung, C., Moffatt, T., Megarry, K., Thomas, K., Mitchell, P., Wallace, J. M. W., Pourshahidi, L. K., Ternan, N. G., Corona, G., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Hotchkiss, S., Campbell, R., Moreno-Rojas, J. M., Cuevas, F. J., Pereira-Caro, G., Rowland, I. and Gill, C. I. R. (2018) Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial. American Journal of Clinical Nutrition, 108 (4). pp. 688-700. ISSN 0002-9165 doi: 10.1093/ajcn/nqy147

Marques, C., Fernandes, I., Meireles, M., Faria, A., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Mateus, N. and Calhau, C. (2018) Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins. Scientific Reports, 8 (1). 11341. ISSN 2045-2322 doi: 10.1038/s41598-018-29744-5

Vauzour, D., Corsini, S., Müller, M. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2018) Inhibition of PP2A by hesperetin may contribute to Akt and ERK1/2 activation status in cortical neurons. Archives of Biochemistry and Biophysics, 650. pp. 14-21. ISSN 0003-9861 doi: 10.1016/j.abb.2018.04.020

Amini, A. M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2018) Effects of pelargonidin-3-O-glucoside and its metabolites on lipopolysaccharide-stimulated cytokine production by THP-1 monocytes and macrophages. Cytokine, 103. pp. 29-33. ISSN 1096-0023 doi: 10.1016/j.cyto.2017.12.031

Miquel, S., Champ, C., Day, J., Aarts, E., Bahr, B. A., Bakker, M., Bánáti, D., Calabrese, V., Cederholm, T., Cryan, J., Dye, L., Farrimond, J. A., Korosi, A., Layé, S., Maudsley, S., Milenkovic, D., Mohajeri, M. H., Sijben, J., Solomon, A., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Thuret, S., Vanden Berghe, W., Vauzour, D., Vellas, B., Wesnes, K., Willatts, P., Wittenberg, R. and Geurts, L. (2018) Poor cognitive ageing: vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing research reviews, 42. pp. 40-55. ISSN 1568-1637 doi: 10.1016/j.arr.2017.12.004

Ottaviani, J. I., Heiss, C., Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274, Kelm, M. and Schroeter, H. (2018) Recommending flavanols and procyanidins for cardiovascular health: revisited. Molecular Aspects of Medicine. ISSN 0098-2997 doi: 10.1016/j.mam.2018.02.001

Schar, M. Y., Corona, G., Soycan, G., Dine, C., Kristek, A., Alsharif, S. N. S., Behrends, V., Lovegrove, A., Shewry, P. R. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2018) Excretion of avenanthramides, phenolic acids and their major metabolites following intake of oat bran. Molecular Nutrition and Food Research, 62 (2). 1700499. ISSN 1613-4133 doi: 10.1002/mnfr.201700499

Rees, A., Dodd, G. F. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2018) The effects of flavonoids on cardiovascular health: a review of human intervention trials and implications for cerebrovascular function. Nutrients, 10 (12). 1852. ISSN 2072-6643 doi: 10.3390/nu10121852

Mills, C. E. ORCID: https://orcid.org/0000-0002-8313-3700, Flury, A., Marmet, C., Poquet, L., Rimaldi, S. F., Sartori, C., Rexhag, E., Brenner, R., Allman, Y., Zimmerman, D., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Mottram, D. S., Oruna-Concha, M.-J. ORCID: https://orcid.org/0000-0001-7916-1592, Actis-Goretta, L. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2017) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: two randomized, controlled, crossover intervention trials. Clinical Nutrition, 36 (6). pp. 1520-1529. ISSN 0261-5614 doi: 10.1016/j.clnu.2016.11.013

Serra, G., Deiana, M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Corona, G. (2017) Olive oil phenolics prevent oxysterol-induced proinflammatory cytokine secretion and reactive oxygen species production in human peripheral blood mononuclear cells, through modulation of p38 and JNK pathways. Molecular Nutrition & Food Research, 61 (12). 1700283. ISSN 1613-4125 doi: 10.1002/mnfr.201700283

Corona, G., Coman, M. M., Guo, Y., Hotchkiss, S., Gill, C., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rowland, I. (2017) Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts. Molecular Nutrition and Food Research, 61 (11). 1700223. ISSN 1613-4133 doi: 10.1002/mnfr.201700223

Amini, A. M., Muzs, K., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2017) Pelargonidin-3-O-glucoside and its metabolites have modest anti-inflammatory effects in human whole blood cultures. Nutrition Research, 46. pp. 88-95. ISSN 1879-0739 doi: 10.1016/j.nutres.2017.09.006

Saibandith, B., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Rowland, I. R. and Commane, D. M. (2017) Olive polyphenols and the metabolic syndrome. Molecules, 22 (7). 1082. ISSN 1420-3049 doi: 10.3390/molecules22071082

Lockyer, S., Rowland, I., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 and Stonehouse, W. (2017) Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial. European Journal of Nutrition, 5 (4). pp. 1421-1432. ISSN 1436-6215 doi: 10.1007/s00394-016-1188-y

Vauzour, D., Camprubi-Robles, M., Miquel-Kergoat, S., Andres-Lacueva, C., Bánáti, D., Barberger-Gateau, P., Bowman, G. L., Caberlotto, L., Clarke, R., Hogervorst, E., Kiliaan, A. J., Lucca, U., Manach, C., Minihane, A.-M., Mitchell, E. S., Perneczky, R., Perry, H., Roussel, A.-M., Schuermans, J., Sijben, J., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Thuret, S., van de Rest, O., Vandewoude, M., Wesnes, K., Williams, R. J., Williams, R. S. B. and Ramirez, M. (2017) Nutrition for the ageing brain: towards evidence for an optimal diet. Ageing research reviews, 35. pp. 222-240. ISSN 1568-1637 doi: 10.1016/j.arr.2016.09.010

Esteban-Fernández, A., Rendeiro, C., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Del Coso, D. G., de Llano, M. D. G., Bartolomé, B. and Moreno-Arribas, M. V. (2017) Neuroprotective effects of selected microbial-derived phenolic metabolites and aroma compounds from wine in human SH-SY5Y neuroblastoma cells and their putative mechanisms of action. Frontiers in Nutrition, 4. 3. ISSN 2296-861X doi: 10.3389/fnut.2017.00003

Sansone, R., Ottaviani, J. I., Rodriguez-Mateos, A., Heinen, Y., Noske, D., Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274, Crozier, A., Merx, M. W., Kelm, M., Schroeter, H. and Heiss, C. (2017) Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies. American Journal of Clinical Nutrition, 105 (2). pp. 352-360. ISSN 0002-9165 doi: 10.3945/ajcn.116.140046

Dong, H., Sargent, L. J., Chatzidiakou, Y., Saunders, C., Harkness, L., Bordenave, N., Rowland, I., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Orange pomace fibre increases a composite scoring of subjective ratings of hunger and fullness in healthy adults. Appetite, 107. pp. 478-405. ISSN 0195-6663 doi: 10.1016/j.appet.2016.08.118

Rendeiro, C., Dong, H., Saunders, C., Harkness, L., Blaze, M., Hou, Y., Belanger, R. L., Corona, G., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2016) Flavanone-rich citrus beverages counteract the transient decline in postprandial endothelial function in humans: a randomised, controlled, double-masked, cross-over intervention study. British Journal of Nutrition, 116 (12). pp. 1999-2010. ISSN 0007-1145 doi: 10.1017/S0007114516004219

Lamport, D. ORCID: https://orcid.org/0000-0002-4592-0439, Pal, D., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Barbosa Boucas, S., Fletcher, J., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 and Butler, L. (2016) The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow: an acute, randomised, placebo controlled crossover trial in healthy young adults. British Journal of Nutrition, 116 (12). pp. 2160-2168. ISSN 1475-2662 doi: 10.1017/S000711451600430X

Ravishankar, D., Corona, G., Hogan, S. M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 (2016) Thioflavones as novel neuroprotective agents. Bioorganic & Medicinal Chemistry, 24 (21). pp. 5513-5520. ISSN 0968-0896 doi: 10.1016/j.bmc.2016.09.006

Alqurashi, R. M., Galante, L. A., Rowland, I. R., Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 and Commane, D. M. (2016) Consumption of a flavonoid-rich acai meal is associated with acute improvements in vascular function and a reduction in total oxidative status in healthy overweight men. American Journal of Clinical Nutrition, 104 (5). pp. 1227-1235. ISSN 0002-9165 doi: 10.3945/ajcn.115.128728

Alanon, M. E., Castle, S. M., Siswanto, P. J., Cifuentes-Gomez, T. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2016) Assessment of flavanol stereoisomers and caffeine and theobromine content in commercial chocolates. Food Chemistry, 208. pp. 177-184. ISSN 0308-8146 doi: 10.1016/j.foodchem.2016.03.116

Esteban-Fernández, A., Gigorro del Coso, D., González de Llano, D., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Bartolomé, B. and Moreno-Arribas, M. V. (2016) Understanding the protective effects of wine components and their metabolites in the brain function. In: 39th World Congress of Vine and Wine, 23 - 28 Oct 2016, Bento Gonçalves, Brazil, 04008. doi: 10.1051/bioconf/20160704008

Alharbi, M. H., Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Dodd, G. F., Saunders, C., Harkness, L., Butler, L. T. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2016) Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males. European Journal of Nutrition, 55 (6). pp. 2021-2029. ISSN 1436-6215 doi: 10.1007/s00394-015-1016-9

Ottaviani, J. I., Borges, G., Momma, T. Y., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Keen, C. L., Crozier, A. and Schroeter, H. (2016) The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives. Scientific reports, 6. 29034. ISSN 2045-2322 doi: 10.1038/srep29034

Dong, H., Rendeiro, C., Kristek, A., Sargent, L. J., Saunders, C., Harkness, L., Rowland, I., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Addition of orange pomace to orange juice attenuates the increases in peak glucose and insulin concentrations after sequential meal ingestion in men with elevated cardiometabolic risk. Journal of Nutrition, 146 (6). pp. 1197-1203. ISSN 1541-6100 doi: 10.3945/jn.115.226001

Corona, G., Ji, Y., Anegboonlap, P., Hotchkiss, S., Gill, C., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rowland, I. (2016) Gastrointestinal modifications and bioavailability of brown seaweed phlorotannins and effects on inflammatory markers. British Journal of Nutrition, 115 (7). pp. 1240-1253. ISSN 1475-2662 doi: 10.1017/S0007114516000210

Esteban-Fernández, A., Corona, G., Vauzour, D. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2016) Neuroprotective effects associated with wine and its phenolic constituents. In: Moreno-Arribas, M. V. and Bartolomé Suáldea, B. (eds.) Wine Safety, Consumer Preference, and Human Health. Springer, pp. 279-292. ISBN 9783319245126 doi: 10.1007/978-3-319-24514-0_14

Neshatdoust, S., Saunders, C., Castle, S. M., Vauzour, D., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Butler, L., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2016) High-flavonoid intake induces cognitive improvement linked to changes in serum brain-derived neurotrophic factor: two randomised,controlled trials. Nutrition and Healthy Ageing, 4 (1). pp. 81-93. ISSN 2451-9502 doi: 10.3233/NHA-1615

Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Pal, D., Moutsiana, C., Field, D. T. ORCID: https://orcid.org/0000-0003-4041-8404, Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Butler, L. T. (2015) The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial. Psychopharmacology, 232 (17). pp. 3327-3234. ISSN 0033-3158 doi: 10.1007/s00213-015-3972-4

Heiss, C., Sansone, R., Karimi, H., Krabbe, M., Schuler, D., Rodriguez Mateos, A., Krämer, T., Cortese-Krott, M. M., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Schroeter, H., Merx, M. W. and Kelm, M. (2015) Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial. AGE, 37 (3). 56. ISSN 0161-9152 doi: 10.1007/s11357-015-9794-9

Mills, C. E. ORCID: https://orcid.org/0000-0002-8313-3700, Touzonis, X., Oruna-Concha, M.-J. ORCID: https://orcid.org/0000-0001-7916-1592, Mottram, D. S., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2015) In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth. British Journal of Nutrition, 113 (8). pp. 1220-1227. ISSN 0007-1145 doi: 10.1017/S0007114514003948

Vogiatzoglou, A., Mulligan, A. A., Bhaniani, A., Lentjes, M. A. H., McTaggart, A., Luben, R. N., Heiss, C., Kelm, M., Merx, M. W., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Schroeter, H., Khaw, K.-T. and Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931 (2015) Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Free Radical Biology and Medicine, 84. pp. 1-10. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2015.03.005

Kean, R. J., Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Dodd, G. F., Freeman, J. ORCID: https://orcid.org/0009-0009-6457-8171, Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Ellis, J., Butler, L. and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2015) Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk randomised, double-blind, placebo-controlled trial in healthy older adults. American Journal of Clinical Nutrition, 101 (3). pp. 506-514. ISSN 0002-9165 doi: 10.3945/ajcn.114.088518

Cifuentes-Gomez, T., Rodriguez-Mateos, A., Gonzalez-Salvador, I., Alañon, M. E. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2015) Factors affecting the absorption, metabolism, and excretion of cocoa flavanols in humans. Journal of Agricultural and Food Chemistry, 63 (35). pp. 7615-7623. ISSN 1520-5118 doi: 10.1021/acs.jafc.5b00443

Rodriguez-Mateos, A., Hezel, M., Aydin, H., Kelm, M., Lundberg, J. O., Weitzberg, E., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Heiss, C. (2015) Interactions between cocoa flavanols and inorganic nitrate: additive effects on endothelial function at achievable dietary amounts. Free Radical Biology and Medicine, 80. pp. 121-128. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2014.12.009

Sansone, R., Rodriguez-Mateos, A., Heuel, J., Falk, D., Schuler, D., Wagstaff, R., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Schroeter, H., Merx, M. W., Kelm, M. and Heiss, C. (2015) Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study. British Journal of Nutrition, 114 (8). pp. 1246-1255. ISSN 0007-1145 doi: 10.1017/S0007114515002822

Eid, N., Osmanova, H., Natchez, C., Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635, Costabile, A., Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476, Rowland, I. and Spencer, J. P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2015) Impact of palm date consumption on microbiota growth and large intestinal health: a randomised, controlled, cross-over, human intervention study. British Journal of Nutrition, 114 (8). pp. 1226-1236. ISSN 1475-2662 doi: 10.1017/S0007114515002780

Lockyer, S., Corona, G., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rowland, I. (2015) Secoiridoids delivered as olive leaf extract induce acute improvements in human vascular function and reduction of an inflammatory cytokine: a randomised, double-blind, placebo-controlled, cross-over trial. British Journal of Nutrition, 114 (01). pp. 75-83. ISSN 0007-1145 doi: 10.1017/S0007114515001269

Toro-Funes, N., Morales-Gutiérrez, F. J., Veciana-Nogués, M. T., Vidal-Carou, M. C., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rodriguez-Mateos, A. (2015) The intracellular metabolism of isoflavones in endothelial cells. Food & Function, 6 (1). pp. 97-107. ISSN 2042-650X doi: 10.1039/c4fo00772g

Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Saunders, C., Butler, L. T. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) Fruits, vegetables, 100% juice, and cognitive function. Nutrition Reviews, 72 (12). pp. 774-789. ISSN 1753-4887 doi: 10.1111/nure.12149

Eid, N., Enani, S., Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635, Corona, G., Costabile, A., Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476, Rowland, I. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) The impact of date palm fruits and their component polyphenols, on gut microbial ecology, bacterial metabolites and colon cancer cell proliferation. Journal of nutritional science, 3. e46. ISSN 2048-6790 doi: 10.1017/jns.2014.16

Vauzour, D., Pinto, J. T., Cooper, A. J. L. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. Biochemical Journal, 463 (1). pp. 41-52. ISSN 0264-6021 doi: 10.1042/BJ20131519

Rendeiro, C., Foley, A., Lau, V. C., Ring, R., Rodriguez-Mateos, A., Vauzour, D., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Regan, C. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats. Neuropharmacology, 79. pp. 335-344. ISSN 0028-3908 doi: 10.1016/j.neuropharm.2013.12.003

de Jager, C. A., Dye, L., de Bruin, E. A., Butler, L., Fletcher, J., Lamport, D. J. ORCID: https://orcid.org/0000-0002-4592-0439, Latulippe, M. E., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Wesnes, K. (2014) Criteria for validation and selection of cognitive tests for investigating the effects of foods and nutrients. Nutrition reviews, 72 (3). pp. 162-179. ISSN 1753-4887 doi: 10.1111/nure.12094

Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, George, T. W., Chong, M. F., Alimbetov, D. S., Jin, Y., Vidal, A., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Kennedy, O. B. ORCID: https://orcid.org/0000-0003-3885-4872, Tuohy, K. M., Minihane, A. M., Gordon, M. H. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2014) Flavonoid-rich fruits and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease – FLAVURS: a randomized controlled trial. American Journal of Clinical Nutrition, 99 (3). pp. 479-489. ISSN 1938-3207 doi: 10.3945/ajcn.113.074237

Eid, N., Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635, Costabile, A., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2014) Polyphenols, glucosinolates, dietary fibre and colon cancer: Understanding the potential of specific types of fruit and vegetables to reduce bowel cancer progression. Nutrition and Aging, 2 (1). pp. 45-67. ISSN 1879-7725 doi: 10.3233/NUA-130029

Vogiatzoglou, A., Mulligan, A. A., Luben, R. N., Lentjes, M. A. H., Heiss, C., Kelm, M., Merx, M. W., Spencer, J. P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Schroeter, H. and Kuhnle, G. G.C. ORCID: https://orcid.org/0000-0002-8081-8931 (2013) Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union. British Journal of Nutrition, 111 (08). pp. 1463-1473. ISSN 0007-1145 doi: 10.1017/S0007114513003930

Wright, B., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments. Food & Function, 4 (12). pp. 1803-1810. ISSN 2042-650X doi: 10.1039/C3FO60272A

Savignac, H. M., Corona, G., Mills, H., Chen, L., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Tzortzis, G. and Burnet, P. W.J. (2013) Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochemistry International, 63 (8). pp. 756-764. ISSN 0197-0186 doi: 10.1016/j.neuint.2013.10.006

Rendeiro, C., Vauzour, D., Rattray, M., Waffo-Téguo, P., Mérillon, J. M., Butler, L. T., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2013) Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS ONE, 8 (5). e63535. ISSN 1932-6203 doi: 10.1371/journal.pone.0063535

Corona, G., Vauzour, D., Hercelin, J., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2013) Phenolic acid intake, delivered via moderate champagne wine consumption, improves spatial working memory via the modulation of hippocampal and cortical protein expression/activation. Antioxidants & Redox Signaling, 19 (4). pp. 1676-1689. ISSN 1523-0864 doi: 10.1089/ars.2012.5142

Chong, M. F.-F., George, T., Alimbetov, D., Jin, Y., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Kennedy, O. ORCID: https://orcid.org/0000-0003-3885-4872, Minihane, A. M., Gordon, M. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2013) Impact of the quantity and flavonoid content of fruits and vegetables on markers of intake in adults with an increased risk of cardiovascular disease: the FLAVURS Trial. European Journal of Nutrition, 52 (1). pp. 361-378. ISSN 1436-6215 doi: 10.1007/s00394-012-0343-3

Eid, N. M. S., Al-Awadi, B., Vauzour, D., Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2013) Effect of cultivar type and ripening on the polyphenol content of date palm fruit. Journal of Agricultural and Food Chemistry, 61 (10). pp. 2453-2460. ISSN 0021-8561 doi: 10.1021/jf303951e

Wright, B., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs. Cardiovascular Research, 97 (1). pp. 13-22. ISSN 0008-6363 doi: 10.1093/cvr/cvs304

Mills, C. ORCID: https://orcid.org/0000-0002-8313-3700, Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592, Mottram, D. S., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2013) The effect of processing on chlorogenic acid content of commercially available coffee. Food Chemistry, 141 (4). pp. 3335-3340. ISSN 0308-8146 doi: 10.1016/j.foodchem.2013.06.014

Rodriguez Mateos, A., Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592, Kwik-Uribe, C., Vidal, A. and Spencer, J. P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2012) Influence of sugar type on the bioavailability of cocoa flavanols. British journal of nutrition, 108 (12). pp. 2243-2250. ISSN 1475-2662 doi: 10.1017/S0007114512000475

Rendeiro, C., Vauzour, D., Kean, R. J., Butler, L. T., Rattray, M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2012) Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology, 223 (3). pp. 319-330. ISSN 0033-3158 doi: 10.1007/s00213-012-2719-8

Vauzour, D., Spilsbury, A., Vafeiadou, K., Rattray, M. and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2012) Modulation of neuroinflammation by dietary flavonoids. In: Gemma, C. (ed.) Neuroinflammation: Pathogenesis, Mechanisms and Management. Nova, pp. 213-236. ISBN 9781619424623

Fox, B., Schantz, J. T., Haigh, R., Wood, M. E., Moore, P. K., Viner, N., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Winyard, P. G. and Whiteman, M. (2012) Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint? Journal of Cellular and Molecular Medicine, 16 (4). pp. 896-910. ISSN 1582-4934 doi: 10.1111/j.1582-4934.2011.01357.x

Hidalgo, M., Oruna-Concha, M. J. ORCID: https://orcid.org/0000-0001-7916-1592, Kolida, S., Walton, G. E. ORCID: https://orcid.org/0000-0001-5426-5635, Kallithraka, S., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 and de Pascual-Teresa, S. (2012) Metabolism of anthocyanins by human gut microflora and their influence on gut bacterial growth. Journal of Agricultural and Food Chemistry, 60 (15). pp. 3882-3890. ISSN 0021-8561 doi: 10.1021/jf3002153

Rendeiro, C., Guerreiro, J. D.T., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2012) Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. Proceedings of the Nutrition Society, 71 (2). pp. 246-262. ISSN 1475-2719 doi: 10.1017/S0029665112000146

Spilsbury, A., Vauzour, D., Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 and Rattray, M. (2012) Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochemical and Biophysical Research Communications, 418. pp. 578-583. ISSN 0006-291X doi: 10.1016/j.bbrc.2012.01.081

Lockyer, S., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 and Rowland, I. (2012) Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action. Nutrition and Aging, 1 (2). pp. 125-140. ISSN 1879-7725 doi: 10.3233/NUA-2012-0011

Vauzour, D., Corona, G., Hercelin, J., Garnotel, R., Gillery, P., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2011) Potential health effects of Champagne wine consumption. Journal of Wine Research, 22 (2). pp. 175-180. ISSN 1469-9672 doi: 10.1080/09571264.2011.603251

Pinto, J., Paiva-Martins, F., Corona, G., Debnam, E. S., Oruna-Concha, M. ORCID: https://orcid.org/0000-0001-7916-1592, Vauzour, D., Gordon, M. and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2011) Absorption and metabolism of olive oil secoiridoids in the small intestine. British Journal of Nutrition, 105 (11). pp. 1607-1618. ISSN 1475-2662 doi: 10.1017/S000711451000526X

Tzounis, X., Rodriguez Mateos, A., Vulevic, J., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Kwik-Uribe, C. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2011) Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study. American Journal of Clinical Nutrition, 93 (1). pp. 62-72. ISSN 1938-3207 doi: 10.3945/ajcn.110.000075

Vauzour, D., Houseman, E.J., George, T.W., Corona, G., Garnotel, R., Jackson, K.G. ORCID: https://orcid.org/0000-0002-0070-3203, Sellier, C., Gillery, P., Kennedy, O.B. ORCID: https://orcid.org/0000-0003-3885-4872, Lovegrove, J.A. ORCID: https://orcid.org/0000-0001-7633-9455 and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers. British Journal of Nutrition, 103 (8). pp. 1168-1178. ISSN 0007-1145 doi: 10.1017/S0007114509992959

Wright, B., Gibson, T., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2010) Platelet-mediated metabolism of the common dietary flavonoid, quercetin. PLoS ONE, 5 (3). e9673. ISSN 1932-6203 doi: 10.1371/journal.pone.0009673

Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain. Proceedings of the Nutrition Society, 69 (2). pp. 244-260. ISSN 0029-6651 doi: 10.1017/S0029665110000054

Vauzour, D., Corona, G. and Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity. Archives of Biochemistry and Biophysics, 501 (1). pp. 106-111. ISSN 0003-9861 doi: 10.1016/j.abb.2010.03.016

Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Butler, L. T., Kennedy, O. B. ORCID: https://orcid.org/0000-0003-3885-4872, Ellis, J. A., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies. Nutrition Research Reviews, 23 (2). pp. 200-229. ISSN 0954-4224 doi: 10.1017/S0954422410000119

Incani, A., Deiana, M., Corona, G., Vafeiadou, K., Vauzour, D., Dessi, M. A. and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol. Molecular Nutrition & Food Research, 54 (6). pp. 788-796. ISSN 1613-4125 doi: 10.1002/mnfr.200900098

Schroeter, H., Heiss, C., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Keen, C. L., Lupton, J. R. and Schmitz, H. H. (2010) Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs. Molecular Aspects of Medicine, 31 (6). pp. 546-557. ISSN 0098-2997 doi: 10.1016/j.mam.2010.09.008

Vauzour, D., Buonfiglio, M., Corona, G., Chirafisi, J., Vafeiadou, K., Angeloni, C., Hrelia, S., Hrelia, P. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes. Molecular Nutrition & Food Research, 54 (4). pp. 532-542. ISSN 1613-4125 doi: 10.1002/mnfr.200900197

Spencer, J. P. ORCID: https://orcid.org/0000-0003-2931-7274 (2010) The impact of fruit flavonoids on memory and cognition. British Journal of Nutrition, 104 (Supple). S40-S47. ISSN 0007-1145 doi: 10.1017/S0007114510003934

Frank, J., George, T. W., Lodge, J. K., Rodriguez-Mateos, A. M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Minihane, A. M. and Rimbach, G. (2009) Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. Journal of Nutrition, 139 (1). pp. 58-62. ISSN 0022-3166 doi: 10.3945/jn.108.096412

Corona, G., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Dessi, M. A. (2009) Extra virgin olive oil phenolics: absorption, metabolism, and biological activities in the GI tract. Toxicology and Industrial Health, 25 (4-5). pp. 285-293. ISSN 0748-2337 doi: 10.1177/0748233709102951

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2009) Flavonoids and brain health: multiple effects underpinned by common mechanisms. Genes and Nutrition, 4 (4). pp. 243-250. ISSN 1555-8932 doi: 10.1007/s12263-009-0136-3

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Vauzour, D. and Rendeiro, C. (2009) Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects. Archives of Biochemistry and Biophysics, 492 (1-2). pp. 1-9. ISSN 0003-9861 doi: 10.1016/j.abb.2009.10.003

Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Kennedy, O. B. ORCID: https://orcid.org/0000-0003-3885-4872, Ellis, J. A., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Butler, L. T. (2009) Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies. Genes and Nutrition, 4 (4). pp. 227-242. ISSN 1555-8932 doi: 10.1007/s12263-009-0135-4

Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M. A. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2009) Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1. Molecular Nutrition & Food Research, 53 (7). pp. 897-903. ISSN 1613-4125 doi: 10.1002/mnfr.200800269

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2009) Nutrients and brain health: an overview. Genes and Nutrition, 4 (4). pp. 225-226. ISSN 1555-8932 doi: 10.1007/s12263-009-0140-7

Vafeiadou, K., Vauzour, D., Lee, H. Y., Rodriguez-Mateos, A., Williams, R. J. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2009) The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Archives of Biochemistry and Biophysics, 484 (1). pp. 100-109. ISSN 0003-9861 doi: 10.1016/j.abb.2009.01.016

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2009) The impact of flavonoids on memory: physiological and molecular considerations. Chemical Society Reviews, 38 (4). pp. 1152-1161. ISSN 0306-0012 doi: 10.1039/b800422f

Rendeiro, C., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Vauzour, D., Butler, L. T., Ellis, J. A. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2009) The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes and Nutrition, 4 (4). pp. 251-270. ISSN 1555-8932 doi: 10.1007/s12263-009-0137-2

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Mohsen, M. M. A., Minihane, A. M. and Mathers, J. C. (2008) Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition research. British Journal of Nutrition, 99 (1). pp. 12-22. ISSN 0007-1145 doi: 10.1017/s0007114507798938

Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, El Mohsen, M. A., Vauzour, D., Rendeiro, C., Butler, L. T., Ellis, J. A., Whiteman, M. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radical Biology and Medicine, 45 (3). pp. 295-305. ISSN 1873-4596 doi: 10.1016/j.freeradbiomed.2008.04.008

Whiteman, M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Szeto, H. H. and Armstrong, J. S. (2008) Do mitochondriotropic antioxidants prevent chlorinative stress-induced mitochondrial and cellular injury? Antioxidants & Redox Signaling, 10 (3). pp. 641-650. ISSN 1523-0864 doi: 10.1089/ars.2007.1879

Tzounis, X., Vulevic, J., Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, George, T., Leonczak, J., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Kwik-Uribe, C. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Flavanol monomer-induced changes to the human faecal microflora. British Journal of Nutrition, 99 (4). pp. 782-792. ISSN 0007-1145 doi: 10.1017/s0007114507853384

Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Food for thought: the role of dietary flavonoids in enhancing human memory, learning and neuro-cognitive performance. Proceedings of the Nutrition Society, 67 (2). pp. 238-252. ISSN 0029-6651 doi: 10.1017/s0029665108007088

Vafeiadou, K., Vauzour, D., Rodriguez-Mateos, A., Whiteman, M., Williams, R. J. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Glial metabolism of quercetin reduces its neurotoxic potential. Archives of Biochemistry and Biophysics, 478 (2). pp. 195-200. ISSN 0003-9861 doi: 10.1016/j.abb.2008.07.014

Whiteman, M. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Loss of 3-chlorotyrosine by inflammatory oxidants: Implications for the use of 3-chlorotyrosine as a bio-marker in vivo. Biochemical and Biophysical Research Communications, 371 (1). pp. 50-53. ISSN 0006-291X doi: 10.1016/j.bbrc.2008.03.153

Rainey-Smith, S., Schroetke, L.W., Bahia, P., Fahmi, A., Skilton, R., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Rice-Evans, C., Rattray, M. and Williams, R.J. (2008) Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neuroscience Letters, 438 (1). pp. 29-33. ISSN 0304-3940 doi: 10.1016/j.neulet.2008.04.056

Vauzour, D., Ravaioli, G., Vafeiadou, K., Rodriguez-Mateos, A., Angeloni, C. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols. Archives of Biochemistry and Biophysics, 476 (2). pp. 145-151. ISSN 0003-9861 doi: 10.1016/j.abb.2008.03.011

Cooper, A. J. L., Pinto, J. T., Krasnikov, B. F., Niatsetskaya, Z. V., Han, Q., Li, J. Y., Vauzour, D. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase. Archives of Biochemistry and Biophysics, 474 (1). pp. 72-81. ISSN 0003-9861 doi: 10.1016/j.abb.2008.02.038

Vauzour, D., Vafeiadou, K., Rodriguez-Mateos, A., Rendeiro, C. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2008) The neuroprotective potential of flavonoids: a multiplicity of effects. Genes and Nutrition, 3 (3-4). pp. 115-126. ISSN 1555-8932 doi: 10.1007/s12263-008-0091-4

Vauzour, D., Vafeiadou, K., Rice-Evans, C., Williams, R. J. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. Journal of Neurochemistry, 103 (4). pp. 1355-1367. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2007.04841.x

Vauzour, D., Vafeiadou, K., Corona, G., Pollard, S. E., Tzounis, X. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Champagne wine polyphenols protect primary cortical neurons against peroxynitrite-induced injury. Journal of Agricultural and Food Chemistry, 55 (8). pp. 2854-2860. ISSN 0021-8561 doi: 10.1021/jf063304z

Schroeter, H., Bahia, P., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Sheppard, O., Rattray, M., Cadenas, E., Rice-Evans, C. and Williams, R.J. (2007) (-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. Journal of Neurochemistry, 101 (6). pp. 1596-1606. ISSN 0022-3042 doi: 10.1111/j.1471-4159.2006.04434.x

Vauzour, D., Vafeiadou, K., Rice-Evans, C., Cadenas, E. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Inhibition of cellular proliferation by the genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway. Archives of Biochemistry and Biophysics, 468 (2). pp. 159-166. ISSN 0003-9861 doi: 10.1016/j.abb.2007.09.021

Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M.A. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochemical and Biophysical Research Communications, 362 (3). pp. 606-611. ISSN 0006-291X doi: 10.1016/j.bbrc.2007.08.049

Vauzour, D., Vafeiadou, K. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols. Biochemical and Biophysical Research Communications, 362 (2). pp. 340-346. ISSN 0006-291X doi: 10.1016/j.bbrc.2007.07.153

Vafeiadou, K., Vauzour, D. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) Neuroinflammation and its modulation by flavonoids. Endocrine, Metabolic & Immune Disorders - Drug Targets, 7 (3). pp. 211-224. ISSN 2212-3873

Angeloni, C., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Leoncini, E., Biagi, P.L. and Hrelia, S. (2007) Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress. Biochimie, 89 (1). pp. 73-82. ISSN 0300-9084 doi: 10.1016/j.biochi.2006.09.006

Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2007) The interactions of flavonoids within neuronal signalling pathways. Genes and Nutrition, 2 (3). pp. 257-273. ISSN 1555-8932 doi: 10.1007/s12263-007-0056-z

Whiteman, M., Chu, S. H., Siau, J. L., Rose, P., Sabapathy, K., Schantz, J. T., Cheung, N. S., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 and Armstrong, J. S. (2007) The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. Cellular Signalling, 19 (4). pp. 705-714. ISSN 0898-6568 doi: 10.1016/j.cellsig.2006.08.019

El Mohsen, M.A., Marks, J., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Moore, K., Debnam, E., Srai, S.K., Rice-Evans, C. and Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. British Journal of Nutrition, 95 (1). pp. 51-58. ISSN 1475-2662 doi: 10.1079/BJN20051596

Hernandez-Montes, E., Pollard, S.E., Vauzour, D., Jofre-Montseny, L., Rota, C., Rimbach, G., Weinberg, P.D. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury. Biochemical and Biophysical Research Communications, 346 (3). pp. 851-859. ISSN 0006-291X doi: 10.1016/j.bbrc.2006.05.197

El Mohsen, M.A., Bayele, H., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476, Debnam, E., Srai, S.K., Rice-Evans, C. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) Distribution of [H-3]trans-resveratrol in rat tissues following oral administration. British Journal of Nutrition, 96 (1). pp. 62-70. ISSN 0007-1145 doi: 10.1079/bjn20061810

Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Abd El Mohsen, M. and Minihane, A.M. (2006) Metabolism of dietary phytochemicals: a review of the metabolic forms identified in humans. Current Topics in Nutraceutical Research, 4 (3-4). pp. 187-203. ISSN 1540-7535

Pollard, S. E., Whiteman, M. and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling. Biochemical and Biophysical Research Communications, 347 (4). pp. 916-923. ISSN 0006-291X doi: 10.1016/j.bbrc.2006.06.153

Whiteman, M., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Zhu, Y.Z., Armstrong, J.S. and Schantz, J.T. (2006) Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappa B-dependent synthesis of prostaglandin E-2 and nitric oxide in chondrogenically differentiated mesenchyrnal progenitor cells. Osteoarthritis and Cartilage, 14 (5). pp. 460-470. ISSN 1063-4584 doi: 10.1016/j.joca.2005.11.002

Corona, G., Tzounis, X., Dessi, M.A., Deiana, M., Debnam, E.S., Visioli, F. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation. Free Radical Research, 40 (6). pp. 647-658. ISSN 1071-5762 doi: 10.1080/10715760500373000

Nguyen, D.T., Hemandez-Montes, E., Vauzour, D., Schonthal, A.H., Rice-Evans, C., Cadenas, E. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) The intracellular genistein metabolite 5,7,3 ',4 '-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway. Free Radical Biology and Medicine, 41 (8). pp. 1225-1239. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2006.06.026

Lee, S.Y.H., Munerol, B., Pollard, S., Youdim, K.A., Pannala, A.S., Kuhnle, G.G.C. ORCID: https://orcid.org/0000-0002-8081-8931, Debnam, E.S., Rice-Evans, C. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth. Free Radical Biology and Medicine, 40 (2). pp. 323-334. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2005.08.031

Pollard, S.E., Kuhnle, G.G.C. ORCID: https://orcid.org/0000-0002-8081-8931, Vauzour, D., Vafeiadou, K., Tzounis, X., Whiteman, M., Rice-Evans, C. and Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 (2006) The reaction of flavonoid metabolites with peroxynitrite. Biochemical and Biophysical Research Communications, 350 (4). pp. 960-968. ISSN 0006-291X doi: 10.1016/j.bbrc.2006.09.131

El Mohsen, M.M.A., Iravani, M.M., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Rose, S., Fahim, A.T., Motawi, T.M.K., Ismail, N.A.F. and Jenner, P. (2005) Age-associated changes in protein oxidation and proteasome activities in rat brain: modulation by antioxidants. Biochemical and Biophysical Research Communications, 336 (2). pp. 386-391. ISSN 0006-291X doi: 10.1016/j.bbrc.2005.07.201

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Kuhnle, G. G. C. ORCID: https://orcid.org/0000-0002-8081-8931, Hajirezaei, M., Mock, H. P., Sonnewald, U. and Rice-Evans, C. (2005) The genotypic variation of the antioxidant potential of different tomato varieties. Free Radical Research, 39 (9). pp. 1005-1016. ISSN 1071-5762 doi: 10.1080/10715760400022293

Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, El Mohsen, M. M. A. and Rice-Evans, C. (2004) Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity. Archives of Biochemistry and Biophysics, 423 (1). pp. 148-161. ISSN 0003-9861 doi: 10.1016/j.abb.2003.11.010

Tortarolo, M., Crossthwaite, A.J., Conforti, L., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Williams, R.J., Bendotti, C. and Rattray, M. (2004) Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. Journal of Neurochemistry, 88 (2). pp. 481-493. ISSN 0022-3042 doi: 10.1046/j.1471-4159.2003.02208.x

Williams, R.J., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rice-Evans, C. (2004) Flavonoids: antioxidants or signalling molecules? Free Radical Biology and Medicine, 36 (7). pp. 838-849. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2004.01.001

Williams, R.J., Spencer, J.P.E. ORCID: https://orcid.org/0000-0003-2931-7274, Goni, F.M. and Rice-Evans, C.A. (2004) Zinc-histidine complex protects cultured cortical neurons against oxidative stress-induced damage. Neuroscience Letters, 371 (2-3). pp. 106-110. ISSN 0304-3940 doi: 10.1016/j.neulet.2004.08.054

Basu-Modak, S., Gordon, M.J., Dobson, L.H., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Rice-Evans, C. and Tyrrell, R.M. (2003) Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts. Free Radical Biology and Medicine, 35 (8). pp. 910-921. ISSN 0891-5849 doi: 10.1016/S0891-5849(03)00436-2

Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274 (2003) Metabolism of tea flavonoids in the gastrointestinal tract. Journal of Nutrition, 133 (10). 3255S-3261S. ISSN 1541-6100

Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Rice-Evans, C. and Williams, R.J. (2003) Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability. The Journal of Biological Chemistry, 278 (37). pp. 34783-34793. ISSN 1083-351X doi: 10.1074/jbc.M305063200

Schroeter, H., Boyd, C., Ahmed, R., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Duncan, R., Rice-Evans, C. and Cadenas, E. (2003) c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochemical Journal, 372 (2). pp. 359-369. ISSN 0264-6021 doi: 10.1042/BJ20030201

Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Kuhnle, G. G. ORCID: https://orcid.org/0000-0002-8081-8931, Williams, R.J. and Rice-Evans, C. (2003) Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites. Biochemical Journal, 372 (1). pp. 173-181. ISSN 0264-6021 doi: 10.1042/BJ20021972

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