The importance of loop length on the stability of i-motif structures

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Gurung, S. P., Schwarz, C., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345 doi: 10.1039/C4CC07279K

Abstract/Summary

Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.

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Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/39189
Identification Number/DOI	10.1039/C4CC07279K
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Optical Spectroscopy (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Medicinal Chemistry Research Group
Publisher	The Royal Society of Chemistry
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Funders:	Biotechnology and Biological Sciences Research Council	The sponsoring bodies who contributed funding for the creation of this item. Example: NERC Example: The Royal Society of Chemistry A pick list of funders may appear as you type in the funder's name in full or as an acronym. Select a correct match to complete the field or type in a new entry in full. For new entries, the full name is preferred.
Projects:	Metal polypyridyl complex interactions with duplex and higher order DNAs Funded by: Biotechnology and Biological Sciences Research Council (BB/K019279/1 - £441,977) Local Lead (PI): Christine Cardin Project Lead: Christine Janet Cardin 1 October 2013 - 30 September 2016	Click Add to select your project (received at Reading) from an autocomplete list.

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Date Deposited:	10 Feb 2015 11:16	Date item deposited into CentAUR
Last Modified:	08 Sep 2024 06:35	Date item last modified

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