Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926, Kirkham, S., Kowalczyk, R. M. ORCID: https://orcid.org/0000-0002-3926-6530, Castelletto, V., Reza, M. and Ruokolainen, J. (2015) Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes. Chemical Communications, 51 (100). pp. 17680-17683. ISSN 1359-7345 doi: 10.1039/C5CC08224B

Abstract/Summary

The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous solution.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/48786
Item Type	Article
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Publisher	The Royal Society of Chemistry
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