Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones

Al-Ani, W., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155 and Cobb, A. J. A. (2016) Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones. Synlett, 27 (1). pp. 17-20. ISSN 0936-5214 doi: 10.1055/s-0035-1560504

Abstract/Summary

This paper describes the use of bifunctional thiourea catalysts in the intramolecular reaction of a nitronate with conjugated ketones to generate the corresponding γ-nitroketones. In contrast to our previous studies in this area, we obtained the cis-functionalized systems as the major diastereoisomers in good yields and reasonable selectivities.

Additional Information	Invited submission to the Prof Steve Ley 70th Birthday celebrations
Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/44844
Identification Number/DOI	10.1055/s-0035-1560504
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Medicinal Chemistry Research Group
Additional Information	Invited submission to the Prof Steve Ley 70th Birthday celebrations
Publisher	Thieme
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