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Grygielska, B., Hughes, C. E. 
ORCID: https://orcid.org/0000-0002-9790-5820 and Watson, S. P.
(2009)
Molecular basis of platelet activation by an alphaIIbbeta3-CHAMPS peptide.
Journal of thrombosis and haemostasis : JTH, 7 (2).
pp. 339-46.
ISSN 1538-7836
Abstract/Summary
The present study demonstrates that the alphaIIb-CHAMPS peptide induces platelet activation through integrin alphaIIbbeta3-dependent and independent pathways with the former mediating tyrosine phosphorylation of FcR gamma-chain and Syk. The use of the alphaIIb-CHAMPS peptide to study integrin alphaIIbbeta3 function is compromised by non-integrin-mediated effects.
| Item Type | Article |
| URI | https://reading-clone.eprints-hosting.org/id/eprint/44579 |
| Item Type | Article |
| Refereed | Yes |
| Divisions | Life Sciences > School of Biological Sciences > Biomedical Sciences |
| Download/View statistics | View download statistics for this item |
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