Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

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Cook, M. T., Smith, S. L. and Khutoryanskiy, V. V. ORCID: https://orcid.org/0000-0002-7221-2630 (2015) Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing. Chemical Communications, 51 (77). pp. 14447-14450. ISSN 1359-7345 doi: 10.1039/C5CC02428E

Abstract/Summary

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion.

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Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/42544
Identification Number/DOI	10.1039/C5CC02428E
Refereed	Yes
Divisions	Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > NMR (CAF) Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Electron Microscopy Laboratory (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
Publisher	The Royal Society of Chemistry
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Funders:	Leverhulme Trust	The sponsoring bodies who contributed funding for the creation of this item. Example: NERC Example: The Royal Society of Chemistry A pick list of funders may appear as you type in the funder's name in full or as an acronym. Select a correct match to complete the field or type in a new entry in full. For new entries, the full name is preferred.
Projects:	Developing in vitro approaches for testing mucoadhesive drug delivery systems Funded by: Leverhulme Trust (RPG-2013-017 - £160,851) Local Lead (PI): Vitaliy Khutoryanskiy 1 August 2013 - 31 July 2016	Click Add to select your project (received at Reading) from an autocomplete list.

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Date Deposited:	14 Sep 2015 09:18	Date item deposited into CentAUR
Last Modified:	22 Nov 2024 02:26	Date item last modified

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