Applying robust control theory to solve problems in bio-medical sciences: study of an apoptotic model

Trujillo, M., Becerra, V. M. and Hadjiloucas, S. ORCID: https://orcid.org/0000-0003-2380-6114 (2014) Applying robust control theory to solve problems in bio-medical sciences: study of an apoptotic model. Journal of Physics Conference Series, 490 (1). 012140. ISSN 1742-6588 doi: 10.1088/1742-6596/490/1/012140

Abstract/Summary

Biological models of an apoptotic process are studied using models describing a system of differential equations derived from reaction kinetics information. The mathematical model is re-formulated in a state-space robust control theory framework where parametric and dynamic uncertainty can be modelled to account for variations naturally occurring in biological processes. We propose to handle the nonlinearities using neural networks.