[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

Smith, C. ORCID: https://orcid.org/0000-0002-5911-5836, Baxendale, I.R., Lanners, S., Hayward, J.J., Smith, S.C. and Ley, S.V. (2007) [3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor. Organic and Biomolecular Chemistry, 5. pp. 1559-1561. ISSN 1477-0520 doi: 10.1039/b702995k

Abstract/Summary

The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.