Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: synthesis of thioureas and in-line titrations

Browne, D.L., O'Brien, M., Koos, P., Cranwell, P. ORCID: https://orcid.org/0000-0001-7156-5576, Polyzos, A. and Ley, S.V. (2012) Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: synthesis of thioureas and in-line titrations. Synlett, 23 (9). pp. 1402-1406. ISSN 1437-2096 doi: 10.1055/s-0031-1290963

Abstract/Summary

A simple tube-in-tube reactor based on the gas-permeable membrane Teflon AF-2400 was used in the continuous flow reaction of gaseous ammonia with isothiocyanates and one isocyanate. A colourimetric in-line titration technique is also reported as a simple method to quantify the amount of ammonia taken up by the solvent in the system.