The effect of pH on the self-assembly of a collagen derived peptide amphiphile

Dehsorkhi, A., Castelletto, V., Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926, Adamcik, J. and Mezzenga, R. (2013) The effect of pH on the self-assembly of a collagen derived peptide amphiphile. Soft Matter, 9 (26). pp. 6033-6036. ISSN 1744-683X doi: 10.1039/c3sm51029h

Abstract/Summary

Transitions in nanostructure driven by pH are observed for a self-assembling peptide amphiphile (PA) with a cationic pentapeptide headgroup. At pH 3, the PA forms flat tape-like structures, while at pH 4 the PA assembles into twisted right handed structures. These twisted structures transform again to flat tape-like structures at pH 7. In complete contrast, spherical micelles are observed at pH 2. These changes in response to pH may be relevant to biological and pharmaceutical applications of this PA in skincare.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/33774
Item Type	Article
Refereed	Yes
Divisions	Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Publisher	Royal Society of Chemistry
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