Application of hydrogen-bond propensity calculations to an indomethacin–nicotinamide (1:1) co-crystal

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Majumder, M., Buckton, G., Rawlinson, C. F., Williams, A. C. orcid id iconORCID: https://orcid.org/0000-0003-3654-7916, Spillman, M. J., Pidcok, E. and Shankland, K. orcid id iconORCID: https://orcid.org/0000-0001-6566-0155 (2013) Application of hydrogen-bond propensity calculations to an indomethacin–nicotinamide (1:1) co-crystal. CrystEngComm, 15. pp. 4041-4044. ISSN 1466-8033 doi: 10.1039/c3ce40367j

Abstract/Summary

The crystal structure of an indomethacin–nicotinamide (1 : 1) cocrystal produced by milling has been determined from laboratory powder X-ray diffraction (PXRD) data. The hydrogen bonding motifs observed in the structure represent one of the most probable of all the possible combinations of donors and acceptors in the constituent molecules.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/32474
Identification Number/DOI 10.1039/c3ce40367j
Refereed Yes
Divisions Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
Publisher Royal Society of Chemistry
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