Reversible thermal transition of polydiacetylene based on KTTKS collagen sequence

Palladino, P., Castelletto, V., Dehsorkhi , A., Stetsenko, D. and Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926 (2012) Reversible thermal transition of polydiacetylene based on KTTKS collagen sequence. Chemical Communications, 48 (78). pp. 9774-9776. ISSN 1359-7345 doi: 10.1039/c2cc34665f

Abstract/Summary

Here we explore the physico-chemical properties of a peptide amphiphile obtained by chemical conjugation of the collagenstimulating peptide KTTKS with 10,12-pentacosadiynoic acid which photopolymerizes as a stable and extended polydiacetylene. We investigate the self-assembly of this new polymer and rationalize its peculiar behavior in terms of a thermal conformational transition. Surprisingly, this polymer shows a thermal transition associated with a non-cooperative increase in b-sheet content at high temperature.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/29268
Item Type	Article
Refereed	Yes
Divisions	Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Electron Microscopy Laboratory (CAF)
Publisher	Royal Society of Chemistry
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