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Anticancer activity of organometallic compounds. 3. The reaction of dimethyltin dichloride with nucleosides under biologically relevant conditions

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Cardin, C. J. orcid id iconORCID: https://orcid.org/0000-0002-2556-9995 and Roy, A. (1986) Anticancer activity of organometallic compounds. 3. The reaction of dimethyltin dichloride with nucleosides under biologically relevant conditions. Inorganica Chimica Acta, 125 (2). pp. 63-66. ISSN 0020-1693 doi: 10.1016/S0020-1693(00)82088-5

Abstract/Summary

This paper reports the reaction of SnMe2Cl2 with adenosine, guanosine and inosine in aqueous solution at pH 4.5. The nucleosides give probably polymeric species in which there is monodentate coordination to O2′ of the ribose ring as indicated by 80 MHz PMR.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/23814
Item Type Article
Refereed Yes
Divisions Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Publisher Elsevier
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