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Aldol reaction of butane-2,3-diacetal protected methyl glycerate

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Fern, S. E., Heath, P. and Cobb, A. J. A. (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi: 10.1016/j.tetasy.2011.01.004

Abstract/Summary

The addition of aldehydes to butane-2,3-diacetal has been investigated. The reaction was shown to be both regioselective and diastereoselective by 1H NMR spectroscopy. The configuration of the newly formed stereocenter was determined by Mosher’s ester analysis.

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Additional Information Dedicated to Professor Steven V. Ley CBE FRS on the occasion of his 65th birthday
Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/16164
Item Type Article
Refereed No
Divisions Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Medicinal Chemistry Research Group
Additional Information Dedicated to Professor Steven V. Ley CBE FRS on the occasion of his 65th birthday
Publisher Elsevier
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