Efficacy of three screening instruments in the identification of autistic-spectrum disorders

Charman, T., Baird, G., Simonoff, E., Loucas, T. ORCID: https://orcid.org/0000-0001-8130-6690, Chandler, S., Meldrum, D. and Pickles, A. (2007) Efficacy of three screening instruments in the identification of autistic-spectrum disorders. British Journal of Psychiatry, 191 (6). pp. 554-559. ISSN 0007-1250 doi: 10.1192/bjp.bp.107.040196

Abstract/Summary

Background Screening instruments for autistic-spectrum disorders have not been compared in the same sample. Aims To compare the Social Communication Questionnaire (SCQ), the Social Responsiveness Scale (SRS) and the Children's Communication Checklist (CCC). Method Screen and diagnostic assessments on 119 children between 9 and 13 years of age with special educational needs with and without autistic-spectrum disorders were weighted to estimate screen characteristics for a realistic target population. Results The SCQ performed best (area under receiver operating characteristic curve (AUC)=0.90; sensitivity. 6; specificity 0.78). The SRS had a lower AUC (0.77) with high sensitivity (0.78) and moderate specificity (0.67). The CCC had a high sensitivity but lower specificity (AUC=0.79; sensitivity 0.93; specificity 0.46). The AUC of the SRS and CCC was lower for children with IQ < 70. Behaviour problems reduced specificity for all three instruments. Conclusions The SCQ, SRS and CCC showed strong to moderate ability to identify autistic-spectrum disorder in this at-risk sample of school-age children with special educational needs.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/14124
Item Type	Article
Refereed	Yes
Divisions	Interdisciplinary centres and themes > ASD (Autism Spectrum Disorders) Research Network Life Sciences > School of Psychology and Clinical Language Sciences
Uncontrolled Keywords	CHILDRENS-COMMUNICATION-CHECKLIST, DIAGNOSTIC INTERVIEW, POPULATION, COHORT, QUESTIONNAIRE, TRAITS, VALIDATION, STRENGTHS, VALIDITY, ROC
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