Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications

Rastall, R.A., Gibson, G.R. ORCID: https://orcid.org/0000-0002-0566-0476, Gill, H.S., Guarner, F., Klaenhammer, T.R., Pot, B., Reid, G., Rowland, I.R. and Sanders, M.E. (2005) Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications. Fems Microbiology Ecology, 52 (2). pp. 145-152. ISSN 0168-6496 doi: 10.1016/j.femsec.2005.01.003

Abstract/Summary

The application of probiotics and prebiotics to the manipulation of the microbial ecology of the human colon has recently seen many scientific advances. The sequencing of probiotic genomes is providing a wealth of new information on the biology of these microorganisms. In addition, we are learning more about the interactions of probiotics with human cells and with pathogenic bacteria. An alternative means of modulating the colonic microbial community is by the use of prebiotic oligosaccharides. Increasing knowledge of the metabolism of prebiotics by probiotics is allowing us to consider specifically targeting such dietary intervention tools at specific populatiori groups and specific disease states. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/13060
Item Type	Article
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Uncontrolled Keywords	probiotics, prebiotics, synbiotics, colonic microbiota, LACTIC-ACID BACTERIA, IN-VITRO EVALUATION, FERMENTATION PROPERTIES, GENOME SEQUENCE, GALACTO-OLIGOSACCHARIDES, GASTROINTESTINAL-TRACT, INTESTINAL MICROFLORA, LACTOBACILLUS-REUTERI, ATOPIC DISEASE, GUT, MICROBIOTA
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