Ventrointermediate thalamic stimulation improves motor learning in humans

Voegtle, A. ORCID: https://orcid.org/0000-0001-5715-2767, Terzic, L., Farahat, A., Hartong, N., Galazky, I., Hinrichs, H., Nasuto, S. J. ORCID: https://orcid.org/0000-0001-9414-9049, de Oliveira Andrade, A. ORCID: https://orcid.org/0000-0002-5689-6606, Knight, R. T. ORCID: https://orcid.org/0000-0001-8686-1685, Ivry, R. B., Voges, J., Deliano, M., Buentjen, L. ORCID: https://orcid.org/0000-0002-9564-4401 and Sweeney-Reed, C. M. ORCID: https://orcid.org/0000-0002-3684-1245 (2024) Ventrointermediate thalamic stimulation improves motor learning in humans. Communications Biology, 7. 798. ISSN 2399-3642 doi: 10.1038/s42003-024-06462-5

Abstract/Summary

Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a repeated sequence. These results highlight the role of thalamo–cortical activity in motor learning.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/120555
Identification Number/DOI	10.1038/s42003-024-06462-5
Refereed	Yes
Divisions	Life Sciences > School of Biological Sciences > Department of Bio-Engineering
Publisher	Nature
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