Peptide fibrillization

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Hamley, I.W. orcid id iconORCID: https://orcid.org/0000-0002-4549-0926 (2007) Peptide fibrillization. Angewandte Chemie-International Edition, 46 (43). pp. 8128-8147. ISSN 1433-7851 doi: 10.1002/anie.200700861

Abstract/Summary

An important factor in many diseases based on the deposition of amyloids is the fibrillization of peptides. Furthermore, fibril formation also promises applications in bionanotechnology: fibrillar peptide hydrogels can be made for cell scaffolds and as substrates for functional and responsive biomaterials, biosensors, and nanowires. The mechanisms and kinetics of fibril formation are discussed.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/11304
Identification Number/DOI 10.1002/anie.200700861
Refereed Yes
Divisions Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Uncontrolled Keywords amyloids, biomaterials, peptides, self-assembly, soft matter , AMYLOID FIBRIL FORMATION, SOLID-STATE NMR, SELF-ASSEMBLING PEPTIDE, X-RAY-DIFFRACTION, FAMILIAL ALZHEIMERS-DISEASE, BETA-LACTOGLOBULIN GELS, HUMAN PRION PROTEIN, DE-NOVO DESIGN, SURFACTANT-LIKE PEPTIDES, HYBRID BLOCK-COPOLYMERS
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