Development of novel small molecules as therapeutics for inflammatory diseases and delineating their molecular mechanisms

Natarajan, N., Ramprasath, T., Gopas, J., Subbiah, R., Rajendran, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, eds. (2022) Development of novel small molecules as therapeutics for inflammatory diseases and delineating their molecular mechanisms. Frontiers in Pharmacology (Special Issue), 13. Frontiers.

Abstract/Summary

During any infection or injury, inflammation plays a vital role in curing the injured tissues. However, uncontrolled inflammatory responses due to defects in pro-resolution and anti-inflammatory processes can be detrimental and lead to many diseases, including gastrointestinal, liver, lung and brain disorders. Although many approved anti-inflammatory drugs are currently in clinical use, long-term usage of anti-inflammatory drugs is associated with many side effects, including gastrointestinal toxicity and adverse effects on the cardiovascular system. Hence, understanding and advancing in the field of small molecules is a better way to tackle this clinical problem with anti-inflammatory drugs. This special issue has collectively published research and review articles focusing on inflammation and small molecule therapeutics with a larger perspective to generate ideas for future scientific and clinical research. We are hopeful that the small molecule-based therapeutic approaches discussed here will evolve more into routine clinical practice in near future.

Additional Information	Special issue of journal Frontiers in Pharmacology, ISSN 1663-9812. Full text is for the editorial.
Item Type	Book
URI	https://reading-clone.eprints-hosting.org/id/eprint/108937
Item Type	Book
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Division of Pharmacology
Additional Information	Special issue of journal Frontiers in Pharmacology, ISSN 1663-9812. Full text is for the editorial.
Publisher	Frontiers
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