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PEGylated systems in pharmaceutics

[thumbnail of 19Aug2020PEGylation review -accepted.pdf]
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Porfiryeva, N. N., Moustafine, R. I. and Khutoryanskiy, V. V. orcid id iconORCID: https://orcid.org/0000-0002-7221-2630 (2020) PEGylated systems in pharmaceutics. Polymer Science Series C, 61 (1). pp. 62-74. ISSN 1811-2382 doi: 10.1134/S181123822001004X

Abstract/Summary

This review addresses the use of poly(ethylene glycol) (PEG) and PEG conjugation for the design of novel dosage forms and the modification of biomolecules. The peculiarities of PEGylated nanoparticles, liposomes, proteins, enzymes, and small drug and polyelectrolyte molecules and their influence on systemic drug delivery, including overcoming of various biological barriers and adhesion to mucosal tissues (mucoadhesion), are considered.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/91652
Item Type Article
Refereed Yes
Divisions Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
Publisher Springer
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