A well-characterised peak identification list of MALDI MS profile peaks for human blood serum

Tiss, A., Smith, C., Menon, U., Jacobs, I., Timms, J. F. and Cramer, R. ORCID: https://orcid.org/0000-0002-8037-2511 (2010) A well-characterised peak identification list of MALDI MS profile peaks for human blood serum. Proteomics, 10 (18). pp. 3388-3392. ISSN 1615-9853 doi: 10.1002/pmic.201000100

Abstract/Summary

MALDI MS profiling, using easily available body fluids such as blood serum, has attracted considerable interest for its potential in clinical applications. Despite the numerous reports on MALDI MS profiling of human serum, there is only scarce information on the identity of the species making up these profiles, particularly in the mass range of larger peptides. Here, we provide a list of more than 90 entries of MALDI MS profile peak identities up to 10 kDa obtained from human blood serum. Various modifications such as phosphorylation were detected among the peptide identifications. The overlap with the few other MALDI MS peak lists published so far was found to be limited and hence our list significantly extends the number of identified peaks commonly found in MALDI MS profiling of human blood serum.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/8227
Identification Number/DOI	10.1002/pmic.201000100
Refereed	Yes
Divisions	Life Sciences Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Uncontrolled Keywords	MALDI / MS/MS peak identification / Serum profiling / Technology
Publisher	WILEY-VCH Verlag
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