Regulation of focal adhesions by PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in cancer cell migration

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Al-Fahad, D. (2018) Regulation of focal adhesions by PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in cancer cell migration. PhD thesis, University of Reading. doi: 10.48683/1926.00079997

Abstract/Summary

Phosphoinositides and their downstream signalling molecules are involved in adhesion, proliferation and invasion. In this study, MDA-MB-231 breast cancer has been used to investigate the possible role of PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in the regulation of FA turnover. Firstly, PtdIns(4,5)P2 and PtdIns(3,4,5)P3 have been visualised by PLC

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Item Type Thesis (PhD)
URI https://reading-clone.eprints-hosting.org/id/eprint/79997
Identification Number/DOI 10.48683/1926.00079997
Divisions Life Sciences > School of Biological Sciences > Biomedical Sciences
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