Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts

Corona, G., Coman, M. M., Guo, Y., Hotchkiss, S., Gill, C., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Rowland, I. (2017) Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts. Molecular Nutrition and Food Research, 61 (11). 1700223. ISSN 1613-4133 doi: 10.1002/mnfr.201700223

Abstract/Summary

Although phlorotannins, TP levels and antioxidant power of the extracts were strongly reduced after in vitro digestion and fermentation, their anti-genotoxic activity and cell growth inhibitory effect in colon HT-29 cells was maintained and enhanced. HMW was the most effective fraction, indicating that the high molecular weight phlorotannins potentially exert a stronger beneficial effect in the colon.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/71528
Identification Number/DOI	10.1002/mnfr.201700223
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
Publisher	Wiley
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