Advanced search

GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.

Download
[thumbnail of Hughan ATVB 2007.pdf]
Text
· Restricted to Repository staff only
· The Copyright of this document has not been checked yet. This may affect its availability.
Restricted to Repository staff only
Advice

Please see our End User Agreement.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

Tools
Add to AnyAdd to TwitterAdd to FacebookAdd to LinkedinAdd to PinterestAdd to Email
Lists

Hughan, S. C., Hughes, C. E. orcid id iconORCID: https://orcid.org/0000-0002-9790-5820, McCarty, O. J. T., Schweighoffer, E., Soultanova, I., Ware, J., Tybulewicz, V. L. J. and Watson, S. P. (2007) GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk. Arteriosclerosis, thrombosis, and vascular biology, 27 (2). pp. 422-9. ISSN 1524-4636

Abstract/Summary

We show that Syk is critical for lamellipodia formation on a range of immobilized proteins but that this can be overcome by addition of thrombin. Further, we reveal a novel role for GPVI in supporting thrombin-induced activation, independent of Syk and Src kinases.

Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/44584
Refereed Yes
Divisions Life Sciences > School of Biological Sciences > Biomedical Sciences
Download/View statistics View download statistics for this item
Deposit Details

University Staff: Request a correction | Centaur Editors: Update this record

Search Google Scholar