Characterisation of amorphous and nanocrystalline molecular materials by total scattering

Billinge, S., Dykhne, T., Juhas, P., Bozin, E., Taylor, R., Florence, A. and Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155 (2010) Characterisation of amorphous and nanocrystalline molecular materials by total scattering. Crystengcomm, 12 (5). pp. 1366-1368. ISSN 1466-8033 doi: 10.1039/b915453a

Abstract/Summary

The use of high-energy X-ray total scattering coupled with pair distribution function analysis produces unique structural fingerprints from amorphous and nanostructured phases of the pharmaceuticals carbamazepine and indomethacin. The advantages of such facility-based experiments over laboratory-based ones are discussed and the technique is illustrated with the characterisation of a melt-quenched sample of carbamazepine as a nanocrystalline (4.5 nm domain diameter) version of form III.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/4410
Item Type	Article
Refereed	Yes
Divisions	Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
Publisher	Royal Society of Chemistry
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