Convergence and accommodation development is pre-programmed in premature infants

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Horwood, A. M. ORCID: https://orcid.org/0000-0003-0886-9686, Toor, S. and Riddell, P. M. ORCID: https://orcid.org/0000-0002-4916-2057 (2015) Convergence and accommodation development is pre-programmed in premature infants. Investigative Ophthalmology & Visual Science, 56. pp. 5370-5380. ISSN 0146-0404 doi: 10.1167/iovs.14-15358

Abstract/Summary

Purpose This study investigated whether vergence and accommodation development in pre-term infants is pre-programmed or is driven by experience. Methods 32 healthy infants, born at mean 34 weeks gestation (range 31.2-36 weeks) were compared with 45 healthy full-term infants (mean 40.0 weeks) over a 6 month period, starting at 4-6 weeks post-natally. Simultaneous accommodation and convergence to a detailed target were measured using a Plusoptix PowerRefII infra-red photorefractor as a target moved between 0.33m and 2m. Stimulus/response gains and responses at 0.33m and 2m were compared by both corrected (gestational) age and chronological (post-natal) age. Results When compared by their corrected age, pre-term and full-term infants showed few significant differences in vergence and accommodation responses after 6-7 weeks of age. However, when compared by chronological age, pre-term infants’ responses were more variable, with significantly reduced vergence gains, reduced vergence response at 0.33m, reduced accommodation gain, and increased accommodation at 2m, compared to full-term infants between 8-13 weeks after birth. Conclusions When matched by corrected age, vergence and accommodation in pre-term infants show few differences from full-term infants’ responses. Maturation appears pre-programmed and is not advanced by visual experience. Longer periods of immature visual responses might leave pre-term infants more at risk of development of oculomotor deficits such as strabismus.

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Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/40636
Identification Number/DOI	10.1167/iovs.14-15358
Refereed	Yes
Divisions	Life Sciences > School of Psychology and Clinical Language Sciences > Department of Psychology Life Sciences > School of Psychology and Clinical Language Sciences > Development Life Sciences > School of Psychology and Clinical Language Sciences > Perception and Action
Uncontrolled Keywords	Convergence Accommodation Development Prematurity Strabismus
Publisher	Association for Research in Vision and Ophthalmology
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Funders:	Medical Research Council	The sponsoring bodies who contributed funding for the creation of this item. Example: NERC Example: The Royal Society of Chemistry A pick list of funders may appear as you type in the funder's name in full or as an acronym. Select a correct match to complete the field or type in a new entry in full. For new entries, the full name is preferred.
Projects:	Typical and atypical ocular accommodation and convergence characteristics and relationships over the life span Funded by: Medical Research Council (G0802809 - £565,793) Local Lead (PI): Anna Horwood 31 December 2009 - 31 March 2014	Click Add to select your project (received at Reading) from an autocomplete list.

Deposit Details

Date Deposited:	09 Jul 2015 10:05	Date item deposited into CentAUR
Last Modified:	23 Jun 2024 02:58	Date item last modified

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