Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation?

Stressmann, F. A., Rogers, G. B., Marsh, P., Lilley, A. K., Daniels, T. W. V., Carroll, M. P., Hoffman, L. R., Jones, G., Allen, C. E., Patel, N. ORCID: https://orcid.org/0000-0002-8600-0663, Forbes, B., Tuck, A. and Bruce, K. D. (2011) Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation? Journal of Cystic Fibrosis, 10 (5). pp. 357-365. ISSN 1569-1993 doi: 10.1016/j.jcf.2011.05.002

Abstract/Summary

These findings strongly suggest that CFPE do not generally result from increased bacterial density within the airways. Instead, data presented here are consistent with alternative models of pulmonary exacerbation.