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A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols

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Baxendale, I.R., Ley, S.V., Smith, C. orcid id iconORCID: https://orcid.org/0000-0002-5911-5836 and Tranmer, G.K. (2006) A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols. Chemical Communications. pp. 4835-4837. ISSN 1359-7345 doi: 10.1039/b612197g

Abstract/Summary

A general flow process for the multi-step assembly of peptides has been developed and this procedure has been used to successfully construct a series of Boc, Cbz and Fmoc N-protected dipeptides in excellent yields and purities, including an extension of the method to enable the preparation of a tripeptide derivative.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/37122
Identification Number/DOI 10.1039/b612197g
Refereed Yes
Divisions No Reading authors. Back catalogue items
Publisher The Royal Society of Chemistry
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