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Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

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Berry, D. J., Vimaleswaran, K. S. orcid id iconORCID: https://orcid.org/0000-0002-8485-8930, Whittaker, J. C., Hingorani, A. D. and Hyppönen, E. (2012) Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS ONE, 7 (5). e37465. ISSN 1932-6203

Abstract/Summary

Combining SNPs into allele scores provides a more powerful instrument for MR analysis than a single SNP in isolation. Population stratification and the potential for pleiotropic effects need to be considered in MR studies on vitamin D.

Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/34646
Refereed Yes
Divisions Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
Publisher Public Library of Science
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