Evidence for a genetic interaction in allergy-related responsiveness to vitamin D deficiency

Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930, Cavadino, A. and Hyppönen, E. (2012) Evidence for a genetic interaction in allergy-related responsiveness to vitamin D deficiency. Allergy, 67 (8). pp. 1033-1040. ISSN 1398-9995 doi: 10.1111/j.1398-9995.2012.02856.x

Abstract/Summary

Our study on white European adults was consistent with a previous study on children from largely non-white ethnic groups, suggesting that IL4 and MS4A2 genotypes modify the association between VDD and allergy risk. The risk allele in IL4 is present in nearly 90% of white Europeans, while less than a quarter are carriers in some other populations, highlighting the need to consider possible ethnic differences in allergy-related responsiveness to VDD.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/34645
Item Type	Article
Refereed	Yes
Divisions	Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR) Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
Uncontrolled Keywords	1958 British birth cohort;25-hydroxyvitamin D;allergy;gene × environment interaction;total IgE
Publisher	Wiley
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