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Electrorhythmogenesis and anaesthesia in a physiological mean field theory

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Bojak, I. orcid id iconORCID: https://orcid.org/0000-0003-1765-3502, Liley, D.T.J., Cadusch, P.J. and Cheng, K. (2004) Electrorhythmogenesis and anaesthesia in a physiological mean field theory. Neurocomputing, 58-60. pp. 1197-1202. ISSN 0925-2312 doi: 10.1016/j.neucom.2004.01.185

Abstract/Summary

We solve eight partial-differential, two-dimensional, nonlinear mean field equations, which describe the dynamics of large populations of cortical neurons. Linearized versions of these equations have been used to generate the strong resonances observed in the human EEG, in particular the α-rhythm (8–), with physiologically plausible parameters. We extend these results here by numerically solving the full equations on a cortex of realistic size, which receives appropriately “colored” noise as extra-cortical input. A brief summary of the numerical methods is provided. As an outlook to future applications, we explain how the effects of GABA-enhancing general anaesthetics can be simulated and present first results.

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/32512
Item Type Article
Refereed Yes
Divisions Interdisciplinary Research Centres (IDRCs) > Centre for Integrative Neuroscience and Neurodynamics (CINN)
Uncontrolled Keywords Electroencephalogram; Alpha rhythm; Cortical mean field theory
Publisher Elsevier
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