JAMming the signals

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Gibbins, J. orcid id iconORCID: https://orcid.org/0000-0002-0372-5352 (2012) JAMming the signals. Blood, 119 (14). pp. 3197-3198. ISSN 1528-0020 doi: 10.1182/blood-2012-02-409060

Abstract/Summary

In this issue of Blood, Naik and colleagues have identified a new mechanism used by platelets to inhibit the signals that drive their activation through integrin αIIbβ3,which serves to prevent inappropriate or premature thrombus formation. Comment on: JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets. [Blood. 2012]

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Item Type Article
URI https://reading-clone.eprints-hosting.org/id/eprint/29062
Identification Number/DOI 10.1182/blood-2012-02-409060
Refereed Yes
Divisions Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Life Sciences > School of Biological Sciences > Biomedical Sciences
Uncontrolled Keywords Haemostasis, thrombosis, platelets, integrin, JAM-A
Publisher American Society of Hematology
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