Microwave-assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions

Cook, J., Goodall, G. W., Khutoryanskaya, O. and Khutoryanskiy, V. V. ORCID: https://orcid.org/0000-0002-7221-2630 (2012) Microwave-assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions. Macromolecular Rapid Communications, 33 (4). pp. 332-336. ISSN 1022-1336 doi: 10.1002/marc.201100742

Abstract/Summary

It has been found that hydrogels may be formed by microwave irradiation of aqueous solutions containing appropriate combinations of polymers. This new method of hydrogel synthesis yields sterile hydrogels without the use of monomers, eliminating the need for the removal of unreacted species from the final product. Results for two particularly successful combinations, poly(vinyl alcohol) with either poly(acrylic acid) or poly(methylvinylether-alt-maleic anhydride), are presented. Irradiation using temperatures of 100–150 °C was found to yield hydrogels with large equilibrium swelling degrees of 500–1000 g g−1. Material leached from both types of hydrogel shows little cytotoxicity towards HT29 cells.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/26406
Item Type	Article
Refereed	Yes
Divisions	Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Thermal Analysis (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Electron Microscopy Laboratory (CAF)
Uncontrolled Keywords	biomaterials;crosslinking;hydrogels;microwaves;synthesis
Publisher	Wiley and Sons
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