Amplifying vibrational circular dichroism by manipulation of the electronic manifold

Domingos, S. R., Panman, M. R., Bakker, B. H., Hartl, F. ORCID: https://orcid.org/0000-0002-7013-5360, Buma, W. J. and Woutersen, S. (2012) Amplifying vibrational circular dichroism by manipulation of the electronic manifold. Chemical Communications, 48 (3). pp. 353-355. ISSN 1359-7345 doi: 10.1039/C1CC15369B

Abstract/Summary

Vibrational circular dichroism is a powerful technique to study the stereochemistry of chiral molecules, but often suffers from small signal intensities. Electrochemical modulation of the energies of the electronically excited state manifold is now demonstrated to lead to an order of magnitude enhancement of the differential absorption. Quantum-chemical calculations show that increased mixing between ground and excited states is at the origin of this amplification.