The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus

Hiscox, J.A., Wurm, T., Wilson, L., Britton, P., Cavanagh, D. and Brooks, G. (2001) The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus. Journal of Virology, 75 (1). pp. 506-512. ISSN 0022-538X doi: 10.1128/JVI.75.1.506-512.2001

Abstract/Summary

The coronavirus nucleoprotein (N) has been reported to be involved in various aspects of virus replication. We examined by confocal microscopy the subcellular localization of the avian infectious bronchitis virus N protein both in the absence and in the context of an infected cell and found that N protein localizes both to the cytoplasmic and nucleolar compartments.