Intensive case management for severe psychotic illness: is there a general benefit for patients with complex needs? A secondary analysis of the UK700 trial data

Metcalfe, C., White, I. R., Weaver, T., Ukoumunne, O. C., Harvey, K. ORCID: https://orcid.org/0000-0002-6819-0934, Tattan, T. and Thompson, S. G. (2005) Intensive case management for severe psychotic illness: is there a general benefit for patients with complex needs? A secondary analysis of the UK700 trial data. Social Psychiatry and Psychiatric Epidemiology, 40 (9). pp. 718-724. ISSN 0933-7954 doi: 10.1007/s00127-005-0954-6

Abstract/Summary

The UK700 trial failed to demonstrate an overall benefit of intensive case management (ICM) in patients with severe psychotic illness. This does not discount a benefit for particular subgroups, and evidence of a benefit of ICM for patients of borderline intelligence has been presented. The aim of this study is to investigate whether this effect is part of a general benefit for patients with severe psychosis complicated by additional needs. In the UK700 trial patients with severe psychosis were randomly allocated to ICM or standard case management. For each patient group with complex needs the effect of ICM is compared with that in the rest of the study cohort. Outcome measures are days spent in psychiatric hospital and the admission and discharge rates. ICM may be of benefit to patients with severe psychosis complicated by borderline intelligence or depression, but may cause patients using illicit drugs to spend more time in hospital. There was no convincing evidence of an effect of ICM in a further seven patient groups. ICM is not of general benefit to patients with severe psychosis complicated by additional needs. The benefit of ICM for patients with borderline intelligence is an isolated effect which should be interpreted cautiously until further data are available.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/13934
Item Type	Article
Refereed	Yes
Divisions	Life Sciences > School of Psychology and Clinical Language Sciences
Uncontrolled Keywords	case management, co-morbidity, data interpretation, statistical, hospitalisation, psychotic disorders, randomised controlled trials, STANDARD CASE-MANAGEMENT, BOOTSTRAP
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