Prebiotics and bowel cancer

Walton, G. E. ORCID: https://orcid.org/0000-0001-5426-5635 and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2007) Prebiotics and bowel cancer. Current Topics in Nutraceutical Research, 5 (1). pp. 19-28. ISSN 1540-7535

Abstract/Summary

Bowel cancer is a growing malignancy, with more than a million annual cases reported worldwide. It has been suggested that there is microbial involvement in onset of the disease and that an altered composition has previously been observed in those suffering from the malignancy, compared to healthy counterparts. The use of prebiotic functional foods to modify the colonic microflora may provide a method of reducing genotoxic potential within the colon, whilst offering-Protective strategies in the form of metabolites such as butyrate. The following review highlights some of the studies that demonstrate the potentia role for prebiotics as protective factors against bowel cancer.