Quantifying additional procedures in functionally single-ventricle disease: a national cohort study

Huang, Q. ORCID: https://orcid.org/0000-0003-4456-2999, Ridout, D., Tsang, V., Drury, N. E., Jones, T. J., Bellsham-Revell, H., Hadjicosta, E., Seale, A. N., Mehta, C., Pagel, C., Crowe, S., Espuny Pujol, F. ORCID: https://orcid.org/0000-0001-9085-7400, Franklin, R. C. G. and Brown, K. L. (2024) Quantifying additional procedures in functionally single-ventricle disease: a national cohort study. Annals of Thoracic Surgery Short Reports, 2 (2). pp. 282-286. ISSN 2772-9931 doi: 10.1016/j.atssr.2023.12.001

Abstract/Summary

Background Given their importance as a metric for health care evaluation, this study’s aim was to evaluate the rates of surgical and catheter reinterventions for children with functionally single-ventricle (f-SV) congenital heart disease (CHD) undergoing staged palliation. Methods We undertook a retrospective cohort study of children born with f-SV CHD between 2000 and 2018 in England and Wales, using the national registry, with survival ascertained in 2020. Competing risk analysis was used to describe the incidence of additional procedures that occurred first, during follow-up, accounting for competing events of death or transplantation. Results Of 56,039 patients who received an intervention for CHD, 3307 (5.9%) had f-SV. The largest diagnostic subcategories were hypoplastic left heart syndrome (1266 [38.3%]), tricuspid atresia (448 [13.5%]), and double-inlet left ventricle (328 [9.9%]). During a median follow-up of 5.4 (interquartile range, 0.8-10.8) years, 921 (27.9%) patients had at least 1 additional interstage surgery and 1293 (39.1%) had at least 1 additional interstage catheter intervention. The cumulative incidence of additional surgery at 6 months after stage 1 was 17.6% (95% CI, 16.2%-19.0%); at 2 years after stage 2, 8.3% (7.2%-9.5%); and at 5 years after stage 3, 8.4% (7.0%-9.9%). The cumulative incidence of additional catheter at 6 months after stage 1 was 18.0% (16.6%-19.4%); at 2 years after stage 2, 14.7% (13.3%-16.2%); and at 5 years after stage 3, 23.7% (21.5%-26.0%).

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/118295
Identification Number/DOI	10.1016/j.atssr.2023.12.001
Refereed	Yes
Divisions	No Reading authors. Back catalogue items Science > School of Mathematical, Physical and Computational Sciences > Department of Computer Science
Publisher	Elsevier BV
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