Multiple lyotropic polymorphism of a PEG-peptide diblock copolymer in aqueous solution

Hamley, I.W. ORCID: https://orcid.org/0000-0002-4549-0926, Krysmann, M.J., Castelletto, V. and Noirez, L. (2008) Multiple lyotropic polymorphism of a PEG-peptide diblock copolymer in aqueous solution. Advanced Materials, 20 (23). pp. 4394-4397. ISSN 0935-9648 doi: 10.1002/adma.200800266

Abstract/Summary

Nematic and hexagonal columnar liquid crystal phase formation by a PEG-peptide conjugate is reported. The results are relevant to peptide-polymer Conjugates and bionanomaterial self-assembly (with relevance to PEGylated peptides used in therapeutic applications). The use of modified fragments of the amyloid beta peptide is especially interesting with respect to amyloid fibrillization and its control.