Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm

Senthilkumaran, S., Miller, S. W., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm. Toxins, 14 (4). 260. ISSN 2072-6651 doi: 10.3390/toxins14040260

Abstract/Summary

Russell’s viper (Daboia russelii), one of the ‘Big Four’ venomous snakes in India is responsible for a majority of snakebite-induced deaths and permanent disabilities. Russell’s viper bites are known to induce bleeding/clotting abnormalities as well as myotoxic, nephrotoxic, cytotoxic and neurotoxic envenomation effects. In addition, they have been reported to induce rare envenomation effects such as priapism, sialolithiasis and splenic rupture. However, Russell’s viper bite-induced pseudoaneurysm (PA) has not been previously reported. PA or false aneurysm is a rare phenomenon that occurs in arteries following traumatic injuries includ-ing some animal bites, and it can become a life-threatening condition if not treated promptly. Here, we document two clinical cas-es of Russell’s viper bites where PA has developed despite antivenom treatment. Notably, a non-surgical procedure, ultra-sound-guided compression (USGC), either alone, or in combination with thrombin was effectively used in both the cases to treat the PA. Following this procedure and additional measures, the patients made complete recoveries without the recurrence of PA which were confirmed by subsequent examination and ultrasound scans. These data demonstrate the development of PA as a rare complication following Russell’s viper bites and the effective use of a simple, non-surgical procedure, USGC for the successful treatment of PA. These results will create awareness among healthcare professionals on the development of PA and the use of USGC in snakebite victims following Russell’s viper as well as other viper bites.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/104762
Item Type	Article
Refereed	Yes
Divisions	Life Sciences > School of Biological Sciences > Biomedical Sciences Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Division of Pharmacology Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmacy Practice Research Group
Publisher	MDPI
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