Global urban environmental change drives adaptation in white clover

Santangelo, J. S. ORCID: https://orcid.org/0000-0002-5921-2548, Ness, R. W. ORCID: https://orcid.org/0000-0001-7313-8236, Cohan, B., Fitzpatrick, C. R. ORCID: https://orcid.org/0000-0002-7100-9542, Innes, S. G. ORCID: https://orcid.org/0000-0003-3859-1400, Koch, S., Miles, L. S. ORCID: https://orcid.org/0000-0003-0406-7985, Munim, S., Peres-Neto, P. R. ORCID: https://orcid.org/0000-0002-5629-8067, Prashad, C., Tong, A. T., Aguirre, W. E. ORCID: https://orcid.org/0000-0003-3641-5120, Akinwole, P. O. ORCID: https://orcid.org/0000-0002-4025-9338, Alberti, M., Álvarez, J., Anderson, J. T., Anderson, J. J. ORCID: https://orcid.org/0000-0002-3302-9366, Ando, Y., Andrew, N. R. ORCID: https://orcid.org/0000-0002-2850-2307, Angeoletto, F. ORCID: https://orcid.org/0000-0002-3084-3928, Anstett, D. N. ORCID: https://orcid.org/0000-0001-7552-5539, Anstett, J. ORCID: https://orcid.org/0000-0002-0789-871X, Aoki-Gonçalves, F., Arietta, A. Z. A. ORCID: https://orcid.org/0000-0002-3368-1346, Arroyo, M. T. K., Austen, E. J. ORCID: https://orcid.org/0000-0002-0087-1338, Baena-Díaz, F. ORCID: https://orcid.org/0000-0002-0660-0627, Barker, C. A., Baylis, H. A. ORCID: https://orcid.org/0000-0002-5959-3256, Beliz, J. M., Benitez-Mora, A. ORCID: https://orcid.org/0000-0002-1096-7579, Bickford, D., Biedebach, G., Blackburn, G. S. ORCID: https://orcid.org/0000-0001-9112-5121, Boehm, M. M. A. ORCID: https://orcid.org/0000-0002-2537-3490, Bonser, S. P., Bonte, D. ORCID: https://orcid.org/0000-0002-3320-7505, Bragger, J. R., Branquinho, C. ORCID: https://orcid.org/0000-0001-8294-7924, Brans, K. I. ORCID: https://orcid.org/0000-0002-0464-7720, Bresciano, J. C., Brom, P. D. ORCID: https://orcid.org/0000-0002-9183-438X, Bucharova, A. ORCID: https://orcid.org/0000-0002-5468-5426, Burt, B., Cahill, J. F., Campbell, K. D., Carlen, E. J. ORCID: https://orcid.org/0000-0001-6732-565X, Carmona, D. ORCID: https://orcid.org/0000-0002-4289-8125, Castellanos, M. C. ORCID: https://orcid.org/0000-0002-9967-355X, Centenaro, G. ORCID: https://orcid.org/0000-0001-7999-6186, Chalen, I., Chaves, J. A., Chávez-Pesqueira, M., Chen, X.-Y., Chilton, A. M. ORCID: https://orcid.org/0000-0002-2331-7874, Chomiak, K. M., Cisneros-Heredia, D. F. ORCID: https://orcid.org/0000-0002-6132-2738, Cisse, I. K., Classen, A. T. ORCID: https://orcid.org/0000-0002-6741-3470, Comerford, M. S., Fradinger, C. C., Corney, H., Crawford, A. J., Crawford, K. M. ORCID: https://orcid.org/0000-0003-4421-2243, Dahirel, M. ORCID: https://orcid.org/0000-0001-8077-7765, David, S. ORCID: https://orcid.org/0000-0001-5443-3491, De Haan, R., Deacon, N. J., Dean, C. ORCID: https://orcid.org/0000-0003-0493-1796, del-Val, E. ORCID: https://orcid.org/0000-0003-3862-1024, Deligiannis, E. K., Denney, D. ORCID: https://orcid.org/0000-0001-5732-5656, Dettlaff, M. A., DiLeo, M. F. ORCID: https://orcid.org/0000-0003-0101-5274, Ding, Y.-Y., Domínguez-López, M. E., Dominoni, D. M. ORCID: https://orcid.org/0000-0003-2063-9955, Draud, S. L., Dyson, K. ORCID: https://orcid.org/0000-0002-8860-3396, Ellers, J. ORCID: https://orcid.org/0000-0003-2665-1971, Espinosa, C. I. ORCID: https://orcid.org/0000-0002-5330-4505, Essi, L. ORCID: https://orcid.org/0000-0001-5548-6448, Falahati-Anbaran, M. ORCID: https://orcid.org/0000-0001-6215-6498, Falcão, J. C. F. ORCID: https://orcid.org/0000-0002-3748-0939, Fargo, H. T., Fellowes, M. D. E. ORCID: https://orcid.org/0000-0001-5431-8637, Fitzpatrick, R. M., Flaherty, L. E., Flood, P. J. ORCID: https://orcid.org/0000-0002-7196-9754, Flores, M. F., Fornoni, J. ORCID: https://orcid.org/0000-0002-4157-6431, Foster, A. G., Frost, C. J. ORCID: https://orcid.org/0000-0001-5986-8646, Fuentes, T. L. ORCID: https://orcid.org/0000-0003-2238-2161, Fulkerson, J. R. ORCID: https://orcid.org/0000-0003-2666-9979, Gagnon, E. ORCID: https://orcid.org/0000-0003-3212-9688, Garbsch, F. ORCID: https://orcid.org/0000-0003-0165-9643, Garroway, C. J. ORCID: https://orcid.org/0000-0002-0955-0688, Gerstein, A. C. ORCID: https://orcid.org/0000-0002-0781-9356, Giasson, M. M., Girdler, E. B., Gkelis, S. ORCID: https://orcid.org/0000-0002-7746-3199, Godsoe, W. ORCID: https://orcid.org/0000-0003-1697-6916, Golemiec, A. M. ORCID: https://orcid.org/0000-0002-4764-1302, Golemiec, M., González-Lagos, C. ORCID: https://orcid.org/0000-0001-5679-4610, Gorton, A. J. ORCID: https://orcid.org/0000-0002-4101-2257, Gotanda, K. M. ORCID: https://orcid.org/0000-0002-3666-0700, Granath, G., Greiner, S., Griffiths, J. S. ORCID: https://orcid.org/0000-0003-0319-515X, Grilo, F. ORCID: https://orcid.org/0000-0002-7831-1162, Gundel, P. E. ORCID: https://orcid.org/0000-0003-3246-0282, Hamilton, B., Hardin, J. M., He, T., Heard, S. B., Henriques, A. F. ORCID: https://orcid.org/0000-0003-2800-046X, Hernández-Poveda, M. ORCID: https://orcid.org/0000-0003-1760-6925, Hetherington-Rauth, M. C., Hill, S. J. ORCID: https://orcid.org/0000-0002-3305-6954, Hochuli, D. F. ORCID: https://orcid.org/0000-0002-6673-4475, Hodgins, K. A. ORCID: https://orcid.org/0000-0003-2795-5213, Hood, G. R. ORCID: https://orcid.org/0000-0002-9301-6153, Hopkins, G. R. ORCID: https://orcid.org/0000-0003-1427-5315, Hovanes, K. A. ORCID: https://orcid.org/0000-0001-8994-7863, Howard, A. R. ORCID: https://orcid.org/0000-0002-2203-0214, Hubbard, S. C., Ibarra-Cerdeña, C. N. ORCID: https://orcid.org/0000-0003-4980-4344, Iñiguez-Armijos, C. ORCID: https://orcid.org/0000-0002-9787-3451, Jara-Arancio, P. ORCID: https://orcid.org/0000-0002-5835-2768, Jarrett, B. J. M. ORCID: https://orcid.org/0000-0003-2071-6076, Jeannot, M., Jiménez-Lobato, V. ORCID: https://orcid.org/0000-0003-2050-9026, Johnson, M., Johnson, O., Johnson, P. P. ORCID: https://orcid.org/0000-0003-1930-1834, Johnson, R., Josephson, M. P., Jung, M. C. ORCID: https://orcid.org/0000-0002-7592-1512, Just, M. G. ORCID: https://orcid.org/0000-0003-2493-9269, Kahilainen, A. ORCID: https://orcid.org/0000-0001-9180-6998, Kailing, O. S., Kariñho-Betancourt, E. ORCID: https://orcid.org/0000-0002-5054-7245, Karousou, R. ORCID: https://orcid.org/0000-0003-1794-2101, Kirn, L. A. ORCID: https://orcid.org/0000-0002-8455-3029, Kirschbaum, A. ORCID: https://orcid.org/0000-0002-9379-8765, Laine, A.-L., LaMontagne, J. M. ORCID: https://orcid.org/0000-0001-7713-8591, Lampei, C. ORCID: https://orcid.org/0000-0003-2866-2869, Lara, C., Larson, E. L. ORCID: https://orcid.org/0000-0003-3006-645X, Lázaro-Lobo, A., Le, J. H., Leandro, D. S., Lee, C. ORCID: https://orcid.org/0000-0003-1108-8514, Lei, Y. ORCID: https://orcid.org/0000-0003-4937-2350, León, C. A. ORCID: https://orcid.org/0000-0002-3331-9881, Lequerica Tamara, M. E. ORCID: https://orcid.org/0000-0002-1044-3820, Levesque, D. C. ORCID: https://orcid.org/0000-0001-8745-3827, Liao, W.-J. ORCID: https://orcid.org/0000-0001-7928-9043, Ljubotina, M., Locke, H. ORCID: https://orcid.org/0000-0002-4889-1936, Lockett, M. T., Longo, T. C. ORCID: https://orcid.org/0000-0001-7842-9075, Lundholm, J. T., MacGillavry, T., Mackin, C. R., Mahmoud, A. R., Manju, I. A., Mariën, J. ORCID: https://orcid.org/0000-0001-7600-5594, Martínez, D. N. ORCID: https://orcid.org/0000-0002-5927-4781, Martínez-Bartolomé, M. ORCID: https://orcid.org/0000-0002-1140-943X, Meineke, E. K. ORCID: https://orcid.org/0000-0002-5416-4233, Mendoza-Arroyo, W., Merritt, T. J. S. ORCID: https://orcid.org/0000-0002-4795-7534, Merritt, L. E. L., Migiani, G., Minor, E. S. ORCID: https://orcid.org/0000-0003-3906-3044, Mitchell, N., Mohammadi Bazargani, M. ORCID: https://orcid.org/0000-0002-8526-3824, Moles, A. T. ORCID: https://orcid.org/0000-0003-2041-7762, Monk, J. D. ORCID: https://orcid.org/0000-0002-5214-6576, Moore, C. M. ORCID: https://orcid.org/0000-0001-5783-9833, Morales-Morales, P. A. ORCID: https://orcid.org/0000-0002-9167-6027, Moyers, B. T. ORCID: https://orcid.org/0000-0003-0340-9488, Muñoz-Rojas, M. ORCID: https://orcid.org/0000-0002-9746-5191, Munshi-South, J. ORCID: https://orcid.org/0000-0002-8067-4341, Murphy, S. M., Murúa, M. M. ORCID: https://orcid.org/0000-0002-8777-9445, Neila, M., Nikolaidis, O., Njunjić, I. ORCID: https://orcid.org/0000-0001-5723-4068, Nosko, P. ORCID: https://orcid.org/0000-0002-7444-4988, Núñez-Farfán, J. ORCID: https://orcid.org/0000-0001-5829-8338, Ohgushi, T., Olsen, K. M. ORCID: https://orcid.org/0000-0002-8338-3638, Opedal, Ø. H. ORCID: https://orcid.org/0000-0002-7841-6933, Ornelas, C., Parachnowitsch, A. L. ORCID: https://orcid.org/0000-0001-9668-6593, Paratore, A. S., Parody-Merino, A. M., Paule, J. ORCID: https://orcid.org/0000-0001-5375-7689, Paulo, O. S. ORCID: https://orcid.org/0000-0001-5408-5212, Pena, J. C. ORCID: https://orcid.org/0000-0003-1368-1805, Pfeiffer, V. W. ORCID: https://orcid.org/0000-0002-7284-6975, Pinho, P., Piot, A., Porth, I. M. ORCID: https://orcid.org/0000-0002-9344-6348, Poulos, N., Puentes, A. ORCID: https://orcid.org/0000-0001-9393-7449, Qu, J., Quintero-Vallejo, E. ORCID: https://orcid.org/0000-0002-5222-4837, Raciti, S. M. ORCID: https://orcid.org/0000-0002-6793-5068, Raeymaekers, J. A. M. ORCID: https://orcid.org/0000-0003-2732-7495, Raveala, K. M., Rennison, D. J., Ribeiro, M. C. ORCID: https://orcid.org/0000-0002-4312-202X, Richardson, J. L., Rivas-Torres, G. ORCID: https://orcid.org/0000-0002-2704-8288, Rivera, B. J. ORCID: https://orcid.org/0000-0002-2294-6003, Roddy, A. B. ORCID: https://orcid.org/0000-0002-4423-8729, Rodriguez-Muñoz, E. ORCID: https://orcid.org/0000-0002-0696-2361, Román, J. R. ORCID: https://orcid.org/0000-0002-5324-2033, Rossi, L. S., Rowntree, J. K. ORCID: https://orcid.org/0000-0001-8249-8057, Ryan, T. J. ORCID: https://orcid.org/0000-0003-2039-5989, Salinas, S. ORCID: https://orcid.org/0000-0002-8400-4740, Sanders, N. J., Santiago-Rosario, L. Y. ORCID: https://orcid.org/0000-0002-5403-5650, Savage, A. M. ORCID: https://orcid.org/0000-0001-6239-2933, Scheepens, J.F. ORCID: https://orcid.org/0000-0003-1650-2008, Schilthuizen, M. ORCID: https://orcid.org/0000-0001-6229-0347, Schneider, A. C. ORCID: https://orcid.org/0000-0002-4249-864X, Scholier, T. ORCID: https://orcid.org/0000-0002-0868-1352, Scott, J. L., Shaheed, S. A., Shefferson, R. P., Shepard, C. A., Shykoff, J. A., Silveira, G., Smith, A. D., Solis-Gabriel, L., Soro, A., Spellman, K. V., Whitney, K. S. ORCID: https://orcid.org/0000-0002-0815-5037, Starke-Ottich, I., Stephan, J. G. ORCID: https://orcid.org/0000-0001-6195-7867, Stephens, J. D. ORCID: https://orcid.org/0000-0001-5281-2316, Szulc, J., Szulkin, M. ORCID: https://orcid.org/0000-0002-7355-5846, Tack, A. J. M., Tamburrino, Í. ORCID: https://orcid.org/0000-0002-7163-6220, Tate, T. D., Tergemina, E. ORCID: https://orcid.org/0000-0001-8747-7212, Theodorou, P. ORCID: https://orcid.org/0000-0002-4056-5300, Thompson, K. A. ORCID: https://orcid.org/0000-0002-1487-3254, Threlfall, C. G. ORCID: https://orcid.org/0000-0002-4197-8588, Tinghitella, R. M. ORCID: https://orcid.org/0000-0002-0049-5539, Toledo-Chelala, L., Tong, X. ORCID: https://orcid.org/0000-0002-3474-3043, Uroy, L. ORCID: https://orcid.org/0000-0003-4967-4017, Utsumi, S. ORCID: https://orcid.org/0000-0003-1558-8073, Vandegehuchte, M. L. ORCID: https://orcid.org/0000-0003-1283-4654, VanWallendael, A. ORCID: https://orcid.org/0000-0002-3900-2818, Vidal, P. M., Wadgymar, S. M., Wang, A.-Y. ORCID: https://orcid.org/0000-0001-8217-6146, Wang, N., Warbrick, M. L., Whitney, K. D. ORCID: https://orcid.org/0000-0002-2523-5469, Wiesmeier, M., Wiles, J. T. ORCID: https://orcid.org/0000-0002-5921-3516, Wu, J. ORCID: https://orcid.org/0000-0002-7726-6216, Xirocostas, Z. A. ORCID: https://orcid.org/0000-0001-7103-5153, Yan, Z., Yao, J., Yoder, J. B., Yoshida, O., Zhang, J. ORCID: https://orcid.org/0000-0003-4490-6309, Zhao, Z. ORCID: https://orcid.org/0000-0002-5252-4813, Ziter, C. D. ORCID: https://orcid.org/0000-0002-3731-9678, Zuellig, M. P. ORCID: https://orcid.org/0000-0001-7767-8926, Zufall, R. A. ORCID: https://orcid.org/0000-0001-7534-5941, Zurita, J. E. ORCID: https://orcid.org/0000-0002-6366-7596, Zytynska, S. E. ORCID: https://orcid.org/0000-0002-0174-3303 and Johnson, M. T. J. ORCID: https://orcid.org/0000-0001-9719-0522 (2022) Global urban environmental change drives adaptation in white clover. Science, 375 (6586). pp. 1275-1281. ISSN 0036-8075 doi: 10.1126/science.abk0989

Abstract/Summary

Urbanization transforms environments in ways that alter biological evolution. We examined whether urban environmental change drives parallel evolution by sampling 110,019 white clover plants from 6169 populations in 160 cities globally. Plants were assayed for a Mendelian antiherbivore defense that also affects tolerance to abiotic stressors. Urban-rural gradients were associated with the evolution of clines in defense in 47% of cities throughout the world. Variation in the strength of clines was explained by environmental changes in drought stress and vegetation cover that varied among cities. Sequencing 2074 genomes from 26 cities revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the degree of parallel adaptation varied among cities. Our results demonstrate that urbanization leads to adaptation at a global scale.

Item Type	Article
URI	https://reading-clone.eprints-hosting.org/id/eprint/104156
Identification Number/DOI	10.1126/science.abk0989
Refereed	Yes
Divisions	Life Sciences > School of Biological Sciences > Ecology and Evolutionary Biology
Publisher	AAAS
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